Folate
Mostrando 25-36 de 472 artigos, teses e dissertações.
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25. 5-Methyltetrahydrofolate-homocysteine methyltransferase gene polymorphism (MTR) and risk of head and neck cancer
The functional effect of the A>G transition at position 2756 on the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase), involved in folate metabolism, may be a risk factor for head and neck squamous cell carcinoma (HNSCC). The frequency of MTR A2756G (rs1805087) polymorphism was compared between HNSCC patients and individuals without history
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-05
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26. Folatos, capacidade antioxidante e trans-2-nonenal em cerveja brasileira / Folate, antioxidant capacity and E-2-nonenal in Brazilian beer
In the present study methods were adapted and applied to quantify levels of folate, antioxidant capacity assessment and E-2-nonenal quantification in Brazilian beers. 5 brands of Pilsen, non-alcoholic and Malzbier beers were used, in can and amber bottle. For determination of folates (folic acid - FA, 10-methyl-folic acid - 10Methyl, 5-methyltetrahydrofolate
Publicado em: 2010
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27. Genetics of homocysteine metabolism and associated disorders
Homocysteine is a sulfur-containing amino acid derived from the metabolism of methionine, an essential amino acid, and is metabolized by one of two pathways: remethylation or transsulfuration. Abnormalities of these pathways lead to hyperhomocysteinemia. Hyperhomocysteinemia is observed in approximately 5% of the general population and is associated with an
Publicado em: 2010
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28. Irinotecan and oxaliplain : an overview of the novel chemotherapeutic options for the treatment of advanced colorectal cancer
Colorectal cancer is one of the most frequent malignancies in humans and an important cause of cancer death. Metastatic colorectal cancer remains incurable with available systemic therapeutic options. The most active cytotoxic drug against this malignancy, the antimetabolite 5-fluorouracil, was developed more than forty years ago, and as a single agent produ
Publicado em: 2010
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29. Perfil nutricional de gestantes que receberam orientação dietética: avaliação do ganho ponderal materno total, tipo de parto e resultados perinatais / Nutrition profile of pregnant women who received dietary counseling: assessment of the total maternal weight gain, mode of delivery and perinatal outcomes
This study was carried out at Clínica Obstétrica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, with one hundred eighty-seven pregnant women without comorbidities. This study aimed to know the nutrition profile of pregnant women who received dietary counseling and to evaluate the maternal total weight gain, type of delive
Publicado em: 2010
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30. The effect of 677C>T and 1298A>C MTHFR polymorphisms on sulfasalazine treatment outcome in rheumatoid arthritis
Despite the availability of several new agents for the treatment of rheumatoid arthritis (RA), sulfasalazine remains the mainstay because of both cost and experience with its use. Methylenetetrahydrofolate reductase (MTHFR) is involved in folate metabolism and several polymorphisms have been described in the MTHFR gene. Of these, the 677C>T and 1298A>C polym
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-07
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31. Biofortificação de plantas de alface (Lactuca sativa L.) geneticamente modificadas para aumento do teor de folato
Folate is a complex B vitamin, water-soluble, formed by pterine, para-aminonzoic acid (pABA) and one to eight parts of glutamate. Some studies suggest that its deficiency in pregnant women is related to miscarriage, and that in the foetus it is related to defects of the neural tube, anencephalia, anacephalia, spine bifide, leporine lip and Down syndrome, and
Publicado em: 2009
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32. Consumo alimentar e concentraÃÃes intraeritrocitÃrias de folato em mulheres em idade reprodutiva do Recife/PE, apÃs a regulamentaÃÃo da fortificaÃÃo das farinhas de trigo e milho com ferro e Ãcido fÃlico
O folato à uma vitamina que desempenha importantes funÃÃes no metabolismo humano. A compreensÃo do seu papel metabÃlico vem ganhando destaque na SaÃde PÃblica. Mulheres em idade reprodutiva constituem um grupo vulnerÃvel a deficiÃncia de folato. A fortificaÃÃo de alimentos com Ãcido fÃlico tem sido apontada como uma alternativa para promover aum
Publicado em: 2009
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33. Estabilidade de membrana de eritrócitos em portadores de depressão
A depressão no idoso tem sido apresentada como uma condição neurodegenerativa associada ao ganho de idade, deficiências de folato e/ou cobalamina, elevação nos níveis séricos de homocisteína e alterações na composição e comportamento de membranas biológicas. Com o objetivo de testar a validade das relações entre depressão, envelhecimento, de
Publicado em: 2009
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34. Added sugar consumption in adults and elderly Population-based survey in São Paulo city / Consumo de açúcares de adição entre adultos e idosos: inquérito populacional do município de São Paulo
Scientific evidences point to the undesirable effects of the added sugar in the health, such as: dental caries, excess of energy intake and, consequently, weight gain and dilution of nutrients. The World Health Organization recommends to limit the consumption in 10 % of the energetic intake (EI) from added sugar. In spite of Brazil is one of the principal wo
Publicado em: 2009
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35. Avaliação hemostática e molecular em mulheres com câncer de mama receptor hormonal negativo
The breast cancer is the most common cause of death in women by malignant disease. The mechanisms related to recurrence are unclear, especially the hemostatic alterations that occur during the development of the disease and seem to be related to its aggressiveness. The study had as aim to assess in women with hormone negative receptor breast cancer, in a 24
Publicado em: 2009
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36. Reduced folate carrier 1 (RFC1) is associated with cleft of the lip only
In this report, we have reanalyzed genotyping data in a collection of families from South America based on maternal origin. Genotyping analysis was performed at the Craniofacial Anomalies Research Center at the University of Iowa. These genotypes were derived from genomic DNA samples obtained from blood spots from children born with isolated orofacial clefts
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-08