Evasion
Mostrando 13-24 de 421 artigos, teses e dissertações.
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13. Current approaches to immunotherapy in noncolorectal gastrointestinal malignancies
Noncolorectal gastrointestinal (GI) malignancies are among the most frequently diagnosed cancers. Despite the undeniable progress in systemic treatments in recent decades, further improvements using cytotoxic chemotherapy seem unlikely. In this setting, recent discoveries regarding the mechanism underlying immune evasion have prompted the study of molecules
Clinics. Publicado em: 18/10/2018
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14. Human polyomaviruses and cancer: an overview
The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the capacity of mediating cell transformation and tumorigenesis in different experimental models. The transfo
Clinics. Publicado em: 11/10/2018
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15. Inactivation of phoPQ genes attenuates Salmonella Gallinarum biovar Gallinarum to susceptible chickens
Abstract Salmonella Gallinarum is a host-restrict pathogen that causes fowl typhoid, a severe systemic disease that is one of the major concerns to the poultry industry worldwide. When infecting the bird, SG makes use of evasion mechanisms to survive and to replicate within macrophages. In this context, phoPQ genes encode a two-component regulatory system (P
Braz. J. Microbiol.. Publicado em: 2018-09
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16. Molecular epidemiology of Streptococcus agalactiae isolated from mastitis in Brazilian dairy herds
Abstract Streptococcus agalactiae is one of the most common pathogens leading to mastitis in dairy herds worldwide; consequently, the pathogen causes major economic losses for affected farmers. In this study, multilocus sequence typing (MLST), genotypic capsular typing by multiplex polymerase chain reaction (PCR), and virulence gene detection were performed
Braz. J. Microbiol.. Publicado em: 2017-07
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17. Subversion of immunoproteasome subunit expression in dengue virus serotype 2-infected HepG2 cells
Abstract: INTRODUCTION: Infection with all serotypes of dengue virus (DV) results in augmented antigen presentation by MHC class I molecules. However, the upregulation of immunoproteasome subunits only results from infection with two serotypes. This study aims to elucidate changes in the expression of immunoproteasome subunits resulting from infection with
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-02
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18. Afterword: Evasion of Time: Of Eschaton and Other Illusions
Contexto int.. Publicado em: 2016-12
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19. Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens
Abstract INTRODUCTION The relationships between monocytes and lymphocytes through MHC class II molecules and costimulatory, are of utmost importance for the production of an efficient immune response. In this work, we assessed the expression of surface molecules CD80 and CD86 on CD14+HLA-DR+ monocytes from patients with Chagas disease. METHODS: The study
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-10
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20. Study of surface carbohydrates in Galba truncatula tissues before and after infection with Fasciola hepatica
The presence and distribution of surface carbohydrates in the tissues of Galba truncatula snails uninfected or after infection with Fasciola hepatica as well as on the surface of the snail-pathogenic larval stages of the parasite were studied by lectin labelling assay. This is an attempt to find similarities that indicate possible mimicry, utilised by the pa
Mem. Inst. Oswaldo Cruz. Publicado em: 04/07/2016
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21. Effects of lung cancer cell-associated B7-H1 on T-cell proliferation in vitro and in vivo
B7 homolog 1 (B7-H1) is the most potent immunoinhibitory molecule in the B7 family. In this study, we examined the effects of tumor-associated B7-H1 on T-cell proliferation in lung cancer. The expression of B7-H1 in human adenocarcinoma A549 and mouse Lewis lung carcinoma (LLC) cells were examined by flow cytometry. To assess the in vitro effect of tumor-ass
Braz J Med Biol Res. Publicado em: 20/06/2016
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22. The remarkable journey of adaptation of the Plasmodium falciparum malaria parasite to New World anopheline mosquitoes
Plasmodium falciparum originated in Africa, dispersed around the world as a result of human migration and had to adapt to several different indigenous anopheline mosquitoes. Anophelines from the New World are evolutionary distant form African ones and this probably resulted in a more stringent selection of Plasmodium as it adapted to these vectors. It is tho
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-08
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23. Políticas públicas em cidadania fiscal: análise do comportamento do cidadão usuário do Programa Todos com a Nota, do Governo do Estado de Pernambuco
O objetivo desta pesquisa foi verificar se a Campanha Todos com a Nota – Módulo Esportivo, instituída pelo Governo do Estado de Pernambuco, conscientiza ou não o cidadão acerca da importância social de sempre pedir a nota fiscal nas suas compras sujeitas à incidência do Imposto sobre a Circulação de Mercadorias e Serviços (ICMS), bem como inferir
Publicado em: 01/11/2012
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24. Interação de Leptospira interrogans com o sistema proteolítico plasminogênio/plasmina: análise, caracterização e possíveis implicações na infecção. / Leptospira interrogans interactions with the plasminogen/plasmin proteolytic system: analysis, characterization and possible implications for the infection.
Leptospirosis is a zoonosis caused by pathogenic bacteria from genus Leptospira. Despite its importance, the pathogenicity and virulence remain to be elucidated. The leptospires do not present known proteases able to degrade extracellular matrix, an activity essential for the penetration and dissemination within the hosts. Therefore, we proposed the investig
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/10/2012