Epilepsy
Mostrando 25-36 de 1157 artigos, teses e dissertações.
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25. Aneurisma de aorta torácica em paciente com esclerose tuberosa
Resumo A esclerose tuberosa é uma doença genética de transmissão autossômica dominante. Caracteriza-se, na sua apresentação clássica, por epilepsia, deficiência mental e adenomas sebáceos. Aneurismas de aorta podem acometer desde crianças com poucos meses de vida até adultos jovens portadores de esclerose tuberosa. Apresentamos o caso de uma paci
J. vasc. bras.. Publicado em: 06/06/2019
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26. Guanidinoacetate Methyltransferase Deficiency: A Review of Guanidinoacetate Neurotoxicity
Abstract Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively inherited disorder of the metabolism of creatine that leads to depleted levels of creatine and excessive concentrations of guanidinoacetate (GAA). Patients affected develop neurological symptoms during childhood, such as muscular hypotonia, involuntary extrapyramidal mo
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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27. Epilepsy and Mitochondrial Dysfunction: A Single Center’s Experience
Abstract Epilepsy is a common manifestation of mitochondrial disease. In a large cohort of children and adolescents with mitochondrial disease (n = 180), over 48% of patients developed seizures. The majority (68%) of patients were younger than 3 years and medically intractable (90%). The electroencephalographic pattern of multiregional epileptiform discharge
J. inborn errors metab. screen.. Publicado em: 16/05/2019
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28. Désiré-Magloire Bourneville and his contributions to pediatric neurology
ABSTRACT Désiré-Magloire Bourneville ought to be thought of as the father of Pediatric Neurology for his significant contributions to the field. He worked as a physician, politician, writer, and editor. He was the first to describe the autosomal dominant genetic condition known as “tuberous sclerosis complex”, after conducting an autopsy on a young fem
Arq. Neuro-Psiquiatr.. Publicado em: 13/05/2019
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29. Prevalência e fatores associados à fragilidade em população idosa do Sul do Brasil, 2014
Resumo Objetivo: analisar a prevalência e fatores associados à fragilidade em idosos na cidade de Pelotas, RS, Brasil, em 2014. Métodos: estudo transversal de base populacional incluindo indivíduos com 60 anos ou mais de idade; a fragilidade foi avaliada por uma versão modificada da Escala de Fragilidade de Edmonton; estimaram-se razões de prevalê
Epidemiol. Serv. Saúde. Publicado em: 21/03/2019
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30. Web-Based Undergraduate Medical Education in a Virtual Learning Environment Using an Original Pedagogical Approach: an Observational Longitudinal Study
RESUMO Contexto A educação médica assíncrona via web, em Ambientes de Aprendizagem Virtual (AVA), cresceu muito, em virtude de suas diversas vantagens. Há várias configurações e métodos de instrução disponíveis. As propostas existentes são pouco estruturadas e/ou não são efetivamente utilizadas para o ensino de habilidades de diagnóstico pa
Rev. bras. educ. med.. Publicado em: 2019-03
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31. Micronutrients: Speculation on Inborn Errors, Nutrigenomics, Evolution, the Microbiome, and Nutritional Immunity
Abstract Many micronutrients or cofactors derived from micronutrients are highly reactive, hence their role in catalysis of reactions by enzymes. The concentration of cofactors has to be kept low to avoid unwanted reactions while allowing them to bind to the (apo)enzymes that need them. A new disorder causing B6-responsive epilepsy (proline synthetase cotran
J. inborn errors metab. screen.. Publicado em: 28/02/2019
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32. Central nervous system and analgesic profiles of Lippia genus
Abstract Many people use medicinal plants to relieve disorders related to the central nervous system, such as depression, epilepsy, anxiety and pain, even though the effectiveness of most of them has not yet been proven through scientific studies. Plants of the Lippia genus, Verbenaceae, are widely used in ethnobotany as a food, for seasoning and in antisept
Rev. bras. farmacogn.. Publicado em: 2019-02
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33. Influence of the clinical profile of patients with refractory epilepsy on lamotrigine plasma concentration
ABSTRACT The purpose of this work was to evaluate the influence of the clinical profile on lamotrigine (LTG) plasma concentrations from patients with refractory epileptic seizures. In this cross-sectional study, therapeutic monitoring of LTG, and questionnaires with 75 patients with refractory epileptic seizures of a Hospital in Ribeirão Preto-SP-Brazil wer
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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34. Role of non-coding RNAs in non-aging-related neurological disorders
Protein coding sequences represent only 2% of the human genome. Recent advances have demonstrated that a significant portion of the genome is actively transcribed as non-coding RNA molecules. These non-coding RNAs are emerging as key players in the regulation of biological processes, and act as "fine-tuners" of gene expression. Neurological disorders are cau
Braz J Med Biol Res. Publicado em: 11/06/2018
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35. Deformation of Mitochondrial Cristae in Human Neural Progenitor Cells Exposed to Valproic Acid
ABSTRACT Neural development represents a dynamic process where mitochondrial integrity is decisive for neuronal activity. Structural changes in these organelles may be related to neurological disorders. Valproic acid (VPA) is an anticonvulsive drug commonly used for epilepsy treatment and its use is associated to increased risk of neuropsychiatric disorders.
An. Acad. Bras. Ciênc.. Publicado em: 23/04/2018
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36. Wavelet multiresolution analysis and dyadic scalogram for detection of epileptiform paroxysms in electroencephalographic signals
Abstract Introduction Early detection of epilepsy by the review of large electroencephalographic (EEG) recordings is very stressful, time-consuming, and subjective for neurologists. Several automatic seizure detection systems have been proposed in the literature to solve this problem. Methods This study proposes two complementary wavelet-based approaches f
Res. Biomed. Eng.. Publicado em: 2017-09