Enamel Matrix Proteins
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. In vitro re-hardening of artificial enamel caries lesions using enamel matrix proteins or self-assembling peptides
ABSTRACT Objectives To assess the re-hardening potential of enamel matrix derivatives (EMD) and self-assembling peptides in vitro, hypothesizing that these materials may increase the mineralization of artificial carious lesions and improve hardness profiles. Material and Methods Forty-eight enamel samples were prepared from extracted bovine lower central
J. Appl. Oral Sci.. Publicado em: 2016-02
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2. Novel biological activity of ameloblastin in enamel matrix derivative
Objective Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration. However, the effects of EMD on gingival epithelial cells during regeneration of periodontal tissues are unclear. In this in vitro study, we purified ameloblastin from EMD and investigated its biological effects on epithelial cells. Material and Methods Bi
J. Appl. Oral Sci.. Publicado em: 2015-02
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3. Avaliação clínica do uso das proteínas derivadas da matriz do esmalte e do beta -tricálcio fosfato associado à hidroxiapatita em lesões de bifurcações interproximais classe II / Clinical evaluation of the use of enamel matrix derivative and hydroxyapatite beta tricalcium phosphate composite in the treatment of class II proximal furcation defects
O objetivo do presente estudo foi avaliar, clinicamente, por meio de um estudo prospectivo, randomizado, duplo cego a utilização do ß tricálcio fosfato + hidroxiapatita (HA/ß-TCP) isoladamente ou em combinação com as proteínas derivadas da matriz do esmalte (EMD) no tratamento de lesões de bifurcação interproximais classe II. 30 pacientes, apresen
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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4. The influence of enamel matrix derivate proteins spontaneous periodontal regeneration in rats exposed to cigarette smoke inhalation / Influencia das proteinas derivadas da matriz do esmalte sobre a regeneração periodontal em ratos submetidos a inalação de fumaça de cigarro
Os objetivos do presente estudo foram avaliar, em defeitos do tipo fenestração, não contaminados previamente pelo biofilme dental bacteriano, em ratos, na presença ou na ausência de fumaça de cigarro (IFC): 1- o efeito das proteínas derivadas da matriz do esmalte (PDME) no padrão de cura, histometricamente; 2- o número de osteoclastos na egião dos
Publicado em: 2009
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5. Avaliação do uso das proteinas derivadas da matriz do esmalte no tratamento de lesões de bifurcação proximais classe II : estudo clinico controlado randomizado / Evaluation of the enamel matrix derivate proteins in the treatment of proximal class II furcation involvements. A randomized controlled clinical study
The aim of the present study was to evaluate the clinical response of proximal furcations treated with enamel matrix derived proteins (EMD). Twenty four patients with at least one class II proximal furcation involvements presenting probing depth (PD) ? 5 mm and bleeding on probing were selected. The patients were randomly assigned to: Control Group (n=20) ?
Publicado em: 2007
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6. Desenvolvimento osseo e dentario : aspectos biologicos, bioquimicos e moleculares da remodelação da matriz extracelular regulada pelas metaloproteinases de matriz e seus inibidores / Dental and bone development : biology, biochemistry, and molecular aspects of the matrix metalloproteinases and their inhibitors during extracellular matrix remodeling
Our objective was to analyse the spatial-temporal distribution of MMP-2, MMP-9, TIMP-1, TIMP-2 and RECK during development of mineralized tissue (bone, enamel, and dentine) in embryos, newborn, and adult mice by immunohistochemistry and in situ hybridization. During rat amelogenesis, at the secretion phase, MMPs and RECK were immunostained in the ameloblast
Publicado em: 2007
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7. Utilização de proteinas derivadas da matriz do esmalte (EMDOGAIN) no tratamento de defeitos intra-osseos : estudo longitudinal clinico e radiografico
The aim of the present study was to compare the clinical and radiographical effects of the treatment of intrabony periodontal defects with or without the use of a gel composed of enamel matrix proteins derivative (EMDOGAIN TRADEMARK ). Fifteen patients, exhibiting a total of 19 defects 1 and 2 wall intrabony defects on one-rooted teeth, were randomly divided
Publicado em: 2003
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8. Utilização de proteinas derivadas da matriz do esmalte (EMDOGAIN) no tratamento de defeitos intra-osseos : estudo clinico e radiografico
O objetivo do presente estudo foi comparar, clínica e radiograficamente, o tratamento cirúrgico de defeitos periodontais intra-ósseos com ou sem a utilização de um gel composto por proteínas derivadas da matriz do esmalte (EMDOGAIN@). Dezessete pacientes, apresentando um total de 21 defeitos intra-ósseos interproximais compostos por predominantemente
Publicado em: 2001
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9. Mineralized tissue and vertebrate evolution: The secretory calcium-binding phosphoprotein gene cluster
Gene duplication creates evolutionary novelties by using older tools in new ways. We have identified evidence that the genes for enamel matrix proteins (EMPs), milk caseins, and salivary proteins comprise a family descended from a common ancestor by tandem gene duplication. These genes remain linked, except for one EMP gene, amelogenin. These genes show comm
The National Academy of Sciences.
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10. Genetic basis for the evolution of vertebrate mineralized tissue
Mineralized tissue is vital to many characteristic adaptive phenotypes in vertebrates. Three primary tissues, enamel (enameloid), dentin, and bone, are found in the body armor of ancient agnathans and mammalian teeth, suggesting that these two organs are homologous. Mammalian enamel forms on enamel-specific proteins such as amelogenin, whereas dentin and bon
National Academy of Sciences.
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11. Critical Role of Heparin Binding Domains of Ameloblastin for Dental Epithelium Cell Adhesion and Ameloblastoma Proliferation*
AMBN (ameloblastin) is an enamel matrix protein that regulates cell adhesion, proliferation, and differentiation of ameloblasts. In AMBN-deficient mice, ameloblasts are detached from the enamel matrix, continue to proliferate, and form a multiple cell layer; often, odontogenic tumors develop in the maxilla with age. However, the mechanism of AMBN functions i
American Society for Biochemistry and Molecular Biology.
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12. Construction and identification of mouse amelogenin cDNA clones.
The determination of the biochemical phenotype of tooth epithelium requires specification by the dental mesenchyme. This is a general feature of epithelial-mesenchymal interaction in a number of different epidermal organ systems (e.g., salivary gland, mammary gland, feather, skin, and hair morphogenesis). To investigate these developmental processes, we have