Early Alzheimer Disease
Mostrando 13-24 de 154 artigos, teses e dissertações.
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13. Glicogênio sintase quinase3B e proteína precursora do amilóide em plaquetas de indivíduos com comprometimento cognitivo leve e doença de Alzheimer / Glycogen synthase kinase 3B and amyloid precursor protein in adults platelets with cognitive impairment and Alzheimers disease
Alzheimers disease (AD) is a neurodegenerative disease characterized by progressive decline of memory and other cognitive functions, affecting mainly elderly. The abnormal metabolism of amyloid precursor protein (APP) and protein TAU hyperphosphorylation are cellular hallmarks of this disease. Glycogen synthase kinase 3B (GSK3B) is an enzyme highly expressed
Publicado em: 2010
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14. Cognition and discourse production in Alzheimer's disease: using informative prompts
This article reports an investigation on the cognitive and linguistic mechanisms involved in knowledge management during discourse production of individuals with Alzheimer disease (AD). Two discourse variables were examined, incomplete propositions and repeated propositions. Differences between controls and participants with AD were found concerning the pres
Psychology & Neuroscience. Publicado em: 2009-12
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15. A novel approach based on multiple criteria decision aiding methods to cope with classification problems / A Novel Approach Based on Multiple Criteria Decision Aiding Methods to Cope with Classification Problems
This work presents a novel decision making approach developed upon two Multicriteria Decision Aiding (MCDA) classification methods. The classification methods are centered on the concept of prototypes, that are alternatives that serve as class representatives related to a given problem, and have their performance index very dependent upon the choice of value
Publicado em: 2009
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16. Um modelo híbrido aplicado ao diagnóstico da doença de Alzheimer
Resumo: Devido à elevação da expectativa de vida, ocorre como conseqüência, o aumento da prevalência de demências. A doença de Alzheimer, dentre as demências, é a mais freqüente e responde (isoladamente ou em associação) por cerca de 50% dos casos. Por conta deste quadro e das limitações terapêuticas nos estágios mais avançados da doença,
Publicado em: 2008
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17. Evaluation of prospective memory in patients with mild Alzheimer s disease / Memoria prospectiva em pacientes com doença de alzheimer leve
The prospective memory (PM) is being investigated as one of the types of memory that are earlier impaired in the Alzheimers disease. Our objective in this study was to evaluate the PM in mild DA patients and to check if it is significantly affected in the early stages of the disease. We studied 20 patients with mild AD, with MMSE (Mini-Mental Status Examin
Publicado em: 2008
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18. Short Performance Cognitive Test (SKT): validation study and diagnostic properties in a clinical subjects o folder Brazilian adults / Teste Breve de Perfomance Cognitiva (SKT): estudo de validação e propriedades diagnósticas em uma amostra clínica brasileira
BACKGROUND: The Short Cognitive Performance Test (Syndrom Kurztest, SKT) (Erzigkeit, 2001) is a bedside cognitive screening test capable of detecting deficits that characterize the early stages of dementia, as it evaluates memory and attention skills, taking into account the speed of information processing. The total score provides information about the seve
Publicado em: 2008
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19. Convivência familiar com o idoso acometido pela doença de alzheimer: estudo de caso / Family living with elderly sufferers of Alzheimers Disease: a case study
It consists of a case study of two cases that aims to comprehend the way that families live and cope with elderly sufferers of Alzheimers disease (AD) through the investigation of the family characteristics, the way the diagnostic was perceived and understood by them, their level of information about the disease, received support and the way they cope with t
Publicado em: 2006
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20. Espectroscopia de prótons na doença de Alzheimer e no comprometimento cognitivo sem demência: avaliação de uma amostra da comunidade / Proton spectroscopy in Alzheimer´s disease and cognitive impairment without dementia: a community study
For the description of the proton magnetic resonance spectroscopy (1H-ERM) data in Alzheimer´s disease (AD) and Cognitive Impairment Not Dementia (CIND) in a community set, subjects with AD (n=13), CIND (n=12) and normal control (n=15) were investigated. 1H-ERM was performance with single voxel (8 cm3) placed in temporal, parietal e occipital region and stu
Publicado em: 2005
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21. APOE genotyping and its association with cognitive deficits in children with diarrhea and malnutrition in the Northeast-Brazil / Genotipagem da apolipoproteína E e sua associação com déficits cognitivos em crianças com diarréia e desnutrição no Nordeste do Brasil
Polymorphisms in the apolipoprotein E (APOE) have constituted the major rationale to identify potential risk groups for developing late-onset Alzheimer s disease and help to predict recovery of cognitive function after brain injury. However, the APOE impact on cognitive development in children living in poor areas of the developing world, where we have disco
Publicado em: 2004
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22. O discurso narrativo na doença de Alzheimer
Lnguistic problems are among the initial symptons of Alzheimer s disease (AD), and their presence is a necessary condition to the diagnosis according to the criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). The linguistic studies of patients with AD have been restricted to a lexical-semantic and syntatic analysis, putting aside the
Publicado em: 2000
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23. Practical Principles for the Management of Alzheimer's Disease
Alzheimer's disease is a complex disorder that is particularly challenging to treat and manage. Early recognition of Alzheimer's disease is the first step toward providing patients with optimal therapy and the best opportunity for treatment response. Subsequently, physicians will need to address issues that emerge as the disease inevitably progresses. As the
Physicians Postgraduate Press.
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24. Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia.
Apolipoprotein E (ApoE) plays a key part in lipid metabolism both in the liver, and in the CNS. To clarify the association of ApoE polymorphism with Alzheimer's disease and vascular dementia in Japan, 13 patients with early onset (age > or = 65) sporadic Alzheimer's disease, 40 patients with late onset (age < or = 65) sporadic Alzheimer's disease, 19 patient