Drugs Pre Formulation
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Development of fast dissolving tablets of flurbiprofen by sublimation method and its in vitro evaluation
Flurbiprofen belongs to Biopharmaceutical Classification System (BCS) class II drugs which are poorly soluble in water. The objective of present research work was to prepare fast dissolving tablets of Flurbiprofen using varying concentrations of three different sublimating agents to improve the dissolution rate. Seven formulations were prepared containing di
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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2. Evaluation of skin absorption of drugs from topical and transdermal formulations
ABSTRACT The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a large number of bioactive compounds have been successfully administered via cutaneous administration because of advances in the design of topical and transdermal f
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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3. A green approach for the determination of selected anti-diabetic drugs in pharmaceutical formulation by transmission FTIR spectroscopy
Métodos baseados em espectroscopia de infravermelho com transformada de Fourier (FTIR) para a determinação de duas drogas anti-diabetes, i.e., metformina HCl e glimepirida em formulações de comprimidos, são descritos. Os métodos envolvem o uso de discos de KBr, cautelosamente preparados, com padrões e amostras de metformina HCl e glimepirida. Espectr
J. Braz. Chem. Soc.. Publicado em: 2014-11
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4. Inappropriate surgical chemoprophylaxis and surgical site infection rate at a tertiary care teaching hospital
OBJECTIVES: This study aimed to analyze the pattern of surgical chemoprophylaxis, surgical site infection rate, and to check rationality of surgical chemoprophylaxis based on Kunin's criteria. MATERIALS AND METHODS: A prospective, observational study was performed on patients undergoing surgery, in a tertiary care teaching hospital. Data were collected in a
Braz J Infect Dis. Publicado em: 2013-02
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5. Determinação do perfil farmacocinético de anti-inflamatórios não hormonais aplicados à clinica / Determination of the pharmacokinetic profile of the non-steroidal anti-inflammatory drugs related with clinic outcomes
Objective: The present work aims to evaluation the pharmacokinetic profile of the diclofenac-cholestyramine (140mg capsule) and two pharmaceuticals formulations (100mg tablets and 50mg/m oral suspension) of nimesulide in healthy adult subjects related with clinic outcomes in the hepatic enzymes panel and platelet count. Method: The studies were open, randomi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/08/2011
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6. Estudo de pré-formulação para dose fixa combinada dos tuberculostáticos rifampicina, isoniazida, pirazinamida e etambutol (4 em 1)
De acordo com o quadro mundial da tuberculose, o Brasil ocupa o 18 lugar em número de casos novos, assim o Ministério da Saúde definiu a doença como prioridade entre as Políticas Governamentais de Saúde. Desde então se intensificaram os estudos relacionados ao tratamento e prevenção desta doença. As formulações em dose fixa combinada (DFC) são r
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/02/2010
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7. Prevenção de deficiência: programa de formação para professores Kaingang na terra indígena Ivaí-Paraná
Many health problems and deficiencies of Kaingang indigenous that in many cases are illness sequels, that are the results of occupation process of their lands, where they were obligated to agglomerate themselves in villages without minimum sanitarium conditions putting them in vulnerability situation for many parasitic diseases, bacterial and viral. The cont
Publicado em: 2010
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8. Estudo termoanalítico e de compatibilidade fármaco-excipiente de rifampicina e alguns medicamentos utilizados na terapêutica da tuberculose / Thermoanalytical study and drug-excipient compatibility of rifampicin and some medicines utilized in tuberculosis terapeutics
This work was aimed at implementing the thermal analysis and other physico-chemical and analytical techniques in the development and quality control of drugs and medicines for the treatment of tuberculosis, especially rifampicin. The differential scanning calorimetry (DSC), thermogravimetry/derivative thermogravimetry(TG/DTG), elemental analysis, X-ray diffr
Publicado em: 2007
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9. Concentrações plasmaticas e salivares e efeito sobre a microbiota oral de duas formulações de amoxicilina : estudo em voluntarios sadios
The plasmatic and salivary concentration of amoxicillin(AMO)875mg and its effects on oral microbiota in healthy volunteers were assessed in an open, randomized, two-period crossover designo A single 875 mg oral dose of AMO (Amoxicillin-EMS- test formulation and Amoxil@- reference formulation) was administered to ali volunteers observing 1-week intervaI betwe
Publicado em: 2005