Drug Testing
Mostrando 13-24 de 648 artigos, teses e dissertações.
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13. Staphylococcal slime layers and biofilm from different origins
RESUMO: O gênero Staphylococcus abrange algumas das bactérias patogênicas mais importantes tanto para humanos como para animais. Ele é responsável pela mastite bovina e otite canina, além de estar presente na microbiota de animais e como contaminante em alimentos. Sua patogênese está relacionada à formação de cápsula e biofilme, que contribuem p
Cienc. Rural. Publicado em: 16/05/2019
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14. Speeding up the diagnosis of multidrug-resistant tuberculosis in a high-burden region with the use of a commercial line probe assay
RESUMO Objetivo: Avaliar o diagnóstico rápido de tuberculose multirresistente, utilizando um teste comercial de sondas em linha (LPA-plus), na rotina de um laboratório de referência de tuberculose. Métodos: O teste LPA-plus foi avaliado prospectivamente em 341 isolados simultaneamente submetidos ao teste de suscetibilidade aos antimicrobianos em meio
J. bras. pneumol.. Publicado em: 18/04/2019
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15. Preparation and in vitro & in vivo evaluation of cephalexin matrix tablets
The purpose of the study is to develop cephalexin controlled-release matrix tablets by using lower proportions of release retardant polymer and to establish their in vitro & in vivo correlation. Tablets were compressed by incorporating polymers in a matrix form along with drug which prolong the drug release. Twelve formulations were prepared by mixing ethyl
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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16. Pharmacogenetic testing in oncology: a Brazilian perspective
Pharmacogenetics, a major component of individualized or precision medicine, relies on human genetic diversity. The remarkable developments in sequencing technologies have revealed that the number of genetic variants modulating drug action is much higher than previously thought and that a true personalized prediction of drug response requires attention to ra
Clinics. Publicado em: 11/10/2018
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17. A diagnosis of pulmonary tuberculosis and drug resistance among inmates in Mato Grosso do Sul, Brazil
Abstract INTRODUCTION: High endemic levels of pulmonary tuberculosis in prisons result from overcrowding, limited access to healthcare, delayed diagnosis, sustained transmission owing to poor control measures, and multidrug resistance. This study evaluated locally implemented measures for early pulmonary tuberculosis diagnosis and evaluated resistance to a
Rev. Soc. Bras. Med. Trop.. Publicado em: 2018-06
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18. Fixed drug eruption to nimesulide: an exuberant presentation confirmed by patch testing
An. Bras. Dermatol.. Publicado em: 2018-06
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19. Intratympanic Gentamicin for Intractable Ménière’s Disease - A Review and Analysis of Audiovestibular Impact
Abstract Introduction Intratympanic gentamicin regulates the symptoms in most patients with incapacitating Ménière’s disease. The treatment protocols have changed over the years from medical labyrinthectomy to preservation of vestibular function. Objectives This study aims to review the audiovestibular response related to the effect of the drug in co
Int. Arch. Otorhinolaryngol.. Publicado em: 2018-06
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20. 2,3,8-Trisubstituted Quinolines with Antimalarial Activity
ABSTRACT Combination therapy drugs are considered a fundamental way to control malaria as it mimimizes the risk of emergence of resistance to the individual partner drugs. Consequently, this type of therapy constitutes a driving force for the discovery of new drugs with different modes of action, since this will provide options for combining different drugs
An. Acad. Bras. Ciênc.. Publicado em: 21/05/2018
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21. Pharmacists in dispensing drugs (PharmDisp): protocol for a clinical trial to test the effectiveness of distance education in training pharmacists for dispensing drugs
ABSTRACT Dispensing drug is a moment in which the pharmacist is able to analyze pharmacotherapy and contribute to its rational use. However, research has shown that some pharmacists lack adequate knowledge to perform this service. This study aims to describe a research protocol for a clinical trial to test the effectiveness of a distance learning program to
Braz. J. Pharm. Sci.. Publicado em: 14/05/2018
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22. Prednisone raw material characterization and formulation development
ABSTRACT Solid dosage forms for oral use, particularly tablets, are the most highly used dosage forms in therapy because they are easily administered, have high productivity and relatively low cost and provide a more stable drug to form a semi-solid net. Numerous parameters influence the quality of the final dosage form. In this study, the dissolution profil
Braz. J. Pharm. Sci.. Publicado em: 08/01/2018
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23. Combination of commercially available molecular assays and culture based methods in diagnosis of tuberculosis and drug resistant tuberculosis
ABSTRACT Early diagnosis of tuberculosis is of major clinical importance. Among 4733 clinical specimens collected from 3363 patients and subjected to Ziehl-Neelsen microscopy, 4109 were inoculated onto Löwenstein-Jensen slants and 3139 in Bactec/9000MB. Polymerase Chain Reaction (PCR) was performed in 3139 specimens, whereas, a genotypic assay was directly
Braz. J. Microbiol.. Publicado em: 2017-12
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24. Drug resistance, AmpC-β-lactamase and extended-spectrum β-lactamase-producing Enterobacteriaceae isolated from fish and shrimp
ABSTRACT The present study aims to detect the production of extended-spectrum beta-lactamases (ESBL) by enterobacteria isolated from samples of fresh shrimp and fish obtained from the retail trade of the city of Sobral, Ceará State, Brazil. All bacterial isolates were submitted to identification and antimicrobial susceptibility testing using aminopenicillin
Rev. Inst. Med. trop. S. Paulo. Publicado em: 06/11/2017