Dose Adjusted Therapy
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Screening, diagnosis and management of hypothyroidism in pregnancy: Number 10 – October 2022
Key points Pregnancy places a metabolic overload on the maternal thyroid, especially in the first trimester, mainly because of the demand imposed by the conceptus. The fetal thyroid becomes functionally mature only around pregnancy week 20. Until then, the fetus depends on the transfer of maternal thyroid hormones (THs). Thyroid hormones are essential for
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
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2. Lipid profile and response to statin therapy in patients with hypopituitarism
ABSTRACT Objective: Dyslipidemia is prevalent among patients with hypopituitarism, especially in those with growth hormone (GH) deficiency. This study aimed to evaluate the response to statin therapy among adult patients with dyslipidemia and hypopituitarism. Subjects and methods: A total of 113 patients with hypopituitarism following up at a neuroendocrin
Arch. Endocrinol. Metab.. Publicado em: 2020-12
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3. Short-term renal and metabolic effects of low dose vildagliptin treatment added-on insulin therapy in non-proteinuric patients with type 2 diabetes: open-label randomized prospective study
ABSTRACT Objective The aim of this randomized comparative study was to assess renal and metabolic effects of vildagliptin in insulin-treated type 2 diabetes (T2DM) patients without overt chronic kidney disease. Subjects and methods We randomized 47 insulin-treated non-proteinuric patients with satisfactory controlled T2DM and estimated glomerular filtratio
Arch. Endocrinol. Metab.. Publicado em: 2020-08
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4. Epoetin alfa resistance in hemodialysis patients with chronic kidney disease: a longitudinal study
Anemia is an inevitable complication of hemodialysis, and the primary cause is erythropoietin deficiency. After diagnosis, treatment begins with an erythropoiesis-stimulating agent (ESA). However, some patients remain anemic even after receiving this medication. This study aimed to investigate the factors associated with resistance to recombinant human eryth
Braz J Med Biol Res. Publicado em: 07/05/2018
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5. Ventilator-associated pneumonia: the influence of bacterial resistance, prescription errors, and de-escalation of antimicrobial therapy on mortality rates
Abstract Ventilator-associated pneumonia is the most prevalent nosocomial infection in intensive care units and is associated with high mortality rates (14–70%). Aim This study evaluated factors influencing mortality of patients with Ventilator-associated pneumonia (VAP), including bacterial resistance, prescription errors, and de-escalation of antibiotic
Braz J Infect Dis. Publicado em: 2016-10
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6. Randomized double-blind clinical trial of a new human epoetin versus a commercially available formula for anemia control in patients on hemodialysis
OBJECTIVES: Anemia is a common complication among chronic kidney disease patients on hemodialysis, occurring mostly due to erythropoietin deficiency. This randomized noninferiority trial sought to compare the efficacy and safety of a new epoetin formulation developed by Bio-Manguinhos, a biologics manufacturer affiliated with the Brazilian government, with
Clinics. Publicado em: 2014-08
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7. Effects of different frequencies of transcutaneous electrical nerve stimulation on venous vascular reactivity
Transcutaneous electrical nerve stimulation (TENS) is a type of therapy used primarily for analgesia, but also presents changes in the cardiovascular system responses; its effects are dependent upon application parameters. Alterations to the cardiovascular system suggest that TENS may modify venous vascular response. The objective of this study was to evalua
Braz J Med Biol Res. Publicado em: 2014-05
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8. Abordagem farmacocinética e farmacodinâmica no monitoramento terapêutico de antimicrobianos em pacientes queimados da unidade de terapia intensiva / Pharmacokinetic and pharmacodynamic approach for antimicrobial therapeutic monitoring in burn patients from the intensive care unit
Introdução: A sepse é a maior causa de morbidade e mortalidade em pacientes queimados, uma vez que profundas alterações ocorrem na farmacocinética de agentes antimicrobianos prescritos para o controle das infecções. Além disso, pacientes queimados podem apresentar quadro de infecção por germes da comunidade, numa fase precoce de internação na UT
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/03/2011
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9. AZATIOPRINA NO TRATAMENTO DE PACIENTES COM COLITE ULCERATIVA CÓRTICO-DEPENDENTE: RESULTADOS E FATORES PREDITIVOS DE RESPOSTA
Ulcerative colitis (UC) is a lifelong, immune-mediated inflammatory condition of the colonic mucosa, which is characterized by a relapsing and remitting course. Corticosteroids remain one of the most effective therapies for inducing remission in patients with moderate-to-severe UC. Nonetheless, corticosteroids are not used in maintenance therapy, mainly beca
Publicado em: 2009
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10. "Efeito da colchicina na fibroses hepatica induzida quimicamente em coelhos"
The fibroses development is a fundamental point in the formation of the hepatic cirrhosis, and its comprehension is essential for the understandíng of ~the physiopatology of the cirrhosis and the consequent portal hypertension. The development of an adapted experimental model of hepatic fibroses is useful for the study of the illnesses that may develop the
Publicado em: 1999
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11. Pharmacologic Characteristics of Indinavir, Didanosine, and Stavudine in Human Immunodeficiency Virus-Infected Children Receiving Combination Therapy
The use of human immunodeficiency virus (HIV) protease inhibitors in children has lagged behind that in adults because of the lack of suitable pediatric formulations and information on safe and effective dosing regimens. This study was designed to obtain pharmacokinetic information on indinavir, administered to HIV-infected children also receiving therapy wi
American Society for Microbiology.
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12. Drug dosing guidelines in patients with renal failure.
The metabolism and excretion of many drugs and their pharmacologically active metabolites depend on normal renal function. Accumulation and toxicity can develop rapidly if dosages are not adjusted in patients with impaired renal function. In addition, many drugs that are not dependent on the kidneys for elimination may exert untoward effects in the uremic mi