Dna Protein Interaction
Mostrando 25-36 de 3264 artigos, teses e dissertações.
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25. Síntese, caracterização e estudos de interação de um análogo da antitoxina CcdA empregando fluorescência no estado estacionário
Toxin-antitoxin (TA) systems contribute to plasmid stability by a mechanism called post-segregational killing. The ccd was the first TA system to be discovered with CcdB being the toxin and CcdA the antitoxin. CcdA, an 8.3 kDa protein, interacts with CcdB (11.7 kDa), preventing the cytotoxic activity of CcdB on the DNA gyrase. As an approach to understanding
Química Nova. Publicado em: 2010
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26. Expressão gênica em bibliotecas de cDNA de pele de bovinos F2 (Holandês × Gir) infestados com o carrapato Riphicephalus (Boophilus) microplus / Gene expression in skin cDNA libraries from F2 cattle (Holstein × Gyr) infested with the tick Riphicephalus (Boophilus) microplus
It is known that resistance to cattle tick Riphicephalus (Boophilus) microplus is inheritable and are primarily associated with zebu animals (Bos indicus), although also present at lower levels in some breed taurine (B. taurus). The elucidation of genetic resistance is one of the most promising factors to reduce production losses and to reduce the cost of th
Publicado em: 2009
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27. Characterization of chitinase gene from lutzomyia longipalpis:alternative splicing description and search for promoter sequence / Caracterização de gene de quitinase de Lutzomyia longipalpis: descrição de processamento alternativo e busca por seqüência promotora
Leishmaniasis is a disease caused by Leishmania protozoa transmitted by the bite of infected sand flies. Current methods used to combat this illness have been shown to be inefficient, and better knowledge of aspects related to Leishmania-sand fly interaction are necessary for the development of new controlling methods. A cDNA codifying for a midgutspecific c
Publicado em: 2009
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28. Resistência à ferrugem do cafeeiro: mapeamento genético, físico e análise da expressão gênica em resposta a infecção de H. vastatrix / Coffea leaf rust: genetic, physical mapping and analysis of the gene expression in response to infection the H. vastatrix
The coffee leaf rust it is caused by the biothrofic fungus Hemileia vastatrix is one diseases that more it causes economical damages. The coffee breeding for obtaining for resistance plants it is slow and the moleculars studies of identification for resistance genes to H. vastatrix are still few informative. This study had as objective to obtain information
Publicado em: 2009
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29. Increased expression and purification of soluble iron-regulatory protein 1 from Escherichia coli co-expressing chaperonins GroES and GroEL
Iron is an essential metal for all living organisms. However, iron homeostasis needs to be tightly controlled since iron can mediate the production of reactive oxygen species, which can damage cell components and compromise the integrity and/or cause DNA mutations, ultimately leading to cancer. In eukaryotes, iron-regulatory protein 1 (IRP1) plays a central
Brazilian Journal of Medical and Biological Research. Publicado em: 14/02/2008
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30. Identificação e caracterização de proteinas expressas no espaço intercelular de folhas de Theobroma cacao na interação com Moniliophthora perniciosa / Identification and characterization of proteins expressed in the intercellular space of leves from Theobroma cacao infected by Moniliophthora perniciosa
The invasion of the plant apoplast is a critical phase of the infection for numerous pathogens, including the fungus M. perniciosa (Mp) that remains in the intercellular space at the parasitic stage until about 60 days. Thus, the understanding of plant defenses induced in the apoplasm and the response mechanisms that the pathogens used for bypassing these de
Publicado em: 2008
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31. Identificação de genes expressos durante a fase pré-simbiótica da associação ectomicorrízica entre Hydnangium sp. e Eucalyptus grandis e transformação de fungos ectomicorrízicos / Identification of genes expressed during the pre-symbiotic interaction in the Hydnangium sp.-Eucalyptus grandis ectomycorrhizal association and transformation of ectomycorrhizal fungi
Gene expression in the ectomycorrhizal fungus Hydnangium sp. during the pre-symbiotic interaction was evaluated using an in vitro mycorrhization technique aiming at constructing a suppressive subtractive cDNA library. The fungus was cultivated in the presence of Eucalyptus grandis roots, with no direct physical contact between both organisms. Genes that code
Publicado em: 2008
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32. Interaction between estrogen receptor and retinol-binding protein-4 polymorphisms as a tool for the selection of prolific pigs
The aim of the present study was to investigate the association of the estrogen receptor (ER-PvuII) and retinol-binding protein 4 (RBP4-MspI) gene polymorphisms and their interactions with prolificacy in a commercial synthetic pig line reared in Brazil. A total of 10,374 piglet records from 218 sows and 817 litters were used for litter size analysis. Only fe
Genetics and Molecular Biology. Publicado em: 2008
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33. Estudos de modelagem molecular e relação estrutura atividade da oncoproteína hnRNP K e ligantes / Molecular modeling and structure activity relationship studies of the hnRNP K oncoprotein and ligands.
The Brazilian Project Genoma Câncer (PGHC) supported by FAPESP and the Ludwig Institute for Cancer Research, intended to identify the genes involved in the most common cases of cancer in Brazil. In this project about a million of gene sequences were identified. The major contribution was made in breast, colorectal and head and neck cancers. The results obta
Publicado em: 2008
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34. Caracterização da participação do sistema de ubiquitinação e degradação proteassômica no bloqueio do ciclo celular mediado pela proteína Vpr do HIV-1
HIV-1 Vpr is a viral accessory protein that activates ATR through the induction of DNA replication stress. ATR activation results in cell cycle arrest in G2 and induction of apoptosis. In the present study, we investigate the role of the ubiquitin/proteasome system (UPS) in the above activity of Vpr. We report that the general function of the UPS is required
Publicado em: 2008
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35. FAK interage com MEF2 e ativa região intronica regulatoria do fosfolamban em resposta ao estimulo mecanico / FAK interacts with MEF2 and drives the stretch-induced activation of an intronic enhancer of phospholamban gene in cardiomyocytes
Estudos anteriores demonstraram que em miócitos cardíacos submetidos a estímulos mecânicos ocorre pronta fosforilação e ativação da FAK. Resultados de estudos recentes, realizados em corações de ratos indicaram que em resposta a estímulos mecânicos, a FAK, além de ser ativada, localiza-se no núcleo dos miócitos cardíaco. Estudos conduzidos em
Publicado em: 2008
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36. Análise da expressão gênica no dermatófito Trichophyton rubrum mimetizando a infecção in vitro: pH e diferentes fontes de carbono regulando genes / Analysis of gene expression in the dermatophyte Trichophyton rubrum during the mimetic infection in vitro: pH and carboun sources are regulating genes
Dermatophytes are a group of fungi filamentous that have the ability to invade keratinized substrates, causing dermatophytosis in humans and animals and only penetrate deeper if the host is immunocompromised. Trichophyton rubrum is an anthropophilic and cosmopolitan fungi, the most common agent of superficial mycoses, which uses cell components such as prote
Publicado em: 2008