Displayed Marked Heterogeneity
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Heterogeneidade marcada e referenciaÃÃo / Marked heterogeneity and referentiation
Procedemos, a partir dos pressupostos da LingÃÃstica da EnunciaÃÃo, Ã problematizaÃÃo do quadro das heterogeneidades do tipo mostrada (marcada vs. nÃo-marcada), proposto por Authier-Revuz (1982). Nossa proposta consiste em sugerir que o escopo das ocorrÃncias dos fatos de heterogeneidade marcada seja flexibilizado, de modo a abarcar fenÃmenos de na
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/08/2008
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2. Limited heterogeneity of T cell receptor BV usage in aplastic anemia
Immune mediation of aplastic anemia (AA) has been inferred from clinical responsiveness to immunosuppressive therapies and a large body of circumstantial laboratory evidence. However, neither the immune response nor the nature of the antigens recognized has been well characterized. We established a large number of CD4 and CD8 T cell clones from a patient wit
American Society for Clinical Investigation.
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3. Identification of a chromosomal locus for expression of lipopolysaccharide epitopes in Haemophilus influenzae.
Lipopolysaccharide (LPS) is a major virulence determinant of Haemophilus influenzae. The organism is able to display an extensive repertoire of different LPS structures through the loss and acquisition of multiple oligosaccharide epitopes in various combinations. This marked heterogeneity of LPS molecules has complicated the analysis of the structure of LPS
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4. Differential protein expression and surface presentation generate high-frequency antigenic variation in Mycoplasma fermentans.
Mycoplasma fermentans, a wall-less prokaryote, is currently under investigation as a potential human pathogen. Recently, several surface lipoproteins have been shown to vary in expression between M. fermentans strains. Using specific antibodies to these lipoproteins, we investigated the extent and nature of antigenic variation within this species. Immunoscre
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5. Chemotherapy for Schistosomiasis in Ugandan Fishermen: Treatment Can Cause a Rapid Increase in Interleukin-5 Levels in Plasma but Decreased Levels of Eosinophilia and Worm-Specific Immunoglobulin E
Chemotherapy for blood-dwelling schistosomes kills the worms and exposes parasite antigen to the circulation. In many people from areas of endemicity, this treatment increases parasite-specific immunoglobulin E (IgE) and other Th2 responses in the months following therapy, responses that have been associated with subsequent resistance to reinfection. Here we
American Society for Microbiology.
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6. Analysis of rRNA restriction fragment length polymorphisms from Bacteroides spp. and Bacteroides fragilis isolates associated with diarrhea in humans and animals.
The Escherichia coli rRNA operon rrnB was used as a 32P-labeled hybridization probe in Southern blots of genomic DNAs from representative strains of the saccharolytic, gram-negative, obligate anaerobes of the genus Bacteroides. Control experiments with the B. fragilis type strain ATCC 25285 established that nearly identical rRNA fragment patterns were produc
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7. Interferon Induction as a Quasispecies Marker of Vesicular Stomatitis Virus Populations†
The interferon (IFN)-inducing capacity of different isolates of vesicular stomatitis virus (VSV) of the Indiana (IN) and New Jersey (NJ) serotypes were measured to assess the extent of variability of this phenotype. Over 200 preparations of wild-type field isolates, laboratory strains, and plaque-derived subpopulations were examined. Marked heterogeneity was
American Society for Microbiology.
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8. Processing of α-Globin and ICP0 mRNA in Cells Infected with Herpes Simplex Virus Type 1 ICP27 Mutants
Herpes simplex virus (HSV) ICP27 is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing, polyadenylation, and nuclear export. We have previously reported that ICP27 causes the cytoplasmic accumulation of unspliced α-globin pre-mRNA. Here we examined the effects of a series of ICP27 mutations that alter important f
American Society for Microbiology.
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9. Thrombin-dependent calcium signalling in single human erythroleukaemia cells.
1. A combination of single cell fluorescence and patch clamp techniques were used to study the mechanisms underlying thrombin-evoked Ca2+ signals in human erythroleukaemia (HEL) cells, a leukaemic cell line of platelet-megakaryocyte lineage. 2. Thrombin caused a transient increase in intracellular Ca2+ ([Ca2+]i), consisting of both release of Ca2+ from intra