Defensins
Mostrando 1-12 de 150 artigos, teses e dissertações.
-
1. Impact of smoking on protein levels of beta-defensins in periodontal disease
Resumo Peptídeos antimicrobianos (PAMs) são componentes importantes da resposta do hospedeiro contra patógenos invasores. Além de sua atividade antimicrobiana direta, eles também podem participar da modulação do sistema imunológico. No entanto, o papel dos PAMs na etiopatogenia da doença periodontal e os fatores de risco que podem influenciar a sua
Brazilian Dental Journal. Publicado em: 2022
-
2. Defense-related proteins involved in sugarcane responses to biotic stress
Abstract Sugarcane is one of the most important agricultural crops in the world. However, pathogen infection and herbivore attack cause constant losses in yield. Plants respond to pathogen infection by inducing the expression of several protein types, such as glucanases, chitinases, thaumatins, peptidase inhibitors, defensins, catalases and glycoproteins. Pr
Genet. Mol. Biol.. Publicado em: 20/02/2017
-
3. Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva
Arachnida is the largest class among the arthropods, constituting over 60,000 described species (spiders, mites, ticks, scorpions, palpigrades, pseudoscorpions, solpugids and harvestmen). Many accidents are caused by arachnids, especially spiders and scorpions, while some diseases can be transmitted by mites and ticks. These animals are widely dispersed in u
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/09/2015
-
4. Polimorfismos de genes da imunidade inata associados à infecção pelo HIV-1. / Gene polymorphisms associated innate immunity to HIV-1.
A síndrome da imonodeficiência adquirida (AIDS) é caracterizada pela depleção de linfócitos T CD4+, reduzindo a capacidade do organismo em responder a infecções. Aproximadamente 630 mil pessoas vivem atualmente com o HIV no Brasil, consistindo em um terço dos casos das Américas Central e do Sul. Muitos fatores, como a grande taxa de mutação viral
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2011
-
5. Variable related to the Trypanosoma cruzi (Chagas, 1909) and to the Triatoma brasiliensis vector (Neiva, 1911) that intervenes in the host-parasite relations / Variáveis relacionadas ao Trypanosoma cruzi (Chagas, 1909) e ao vetor Triatoma brasiliensis (Neiva, 1911) que interferem na interação parasito-hospedeiro
Despite of the multiclonal structure and genetical variability of Trypanosoma cruzi (Chagas, 1909), several investigations using the eletrophoretic profiles (zymodeme) and molecular techniques were used to characterize subpopulations of this parasite, further defining two main distinct and distant phylogenetic lineages: T. cruzi (TcI and TcII). In the presen
Publicado em: 2006
-
6. PROTEIN-PROTEIN INTERACTION ANALYSIS OF THE DEFENSIN PSD1 FROM PISUM SATIVUM WITH NEUROSPORA CRASSA PROTEINS / ANÁLISE DA INTERAÇÃO PROTÉICA DA DEFENSINA PSD1 DE PISUM SATIVUM COM PROTEÍNAS DO FUNGO NEUROSPORA CRASSA
Plant defensins, innate components of the plant immune system, are cationic, antifungal peptides, with a cysteine- rich primary structure. Evidence from the literature demonstrated that fungus membrane patches containing complex sphingolipids, mannosyldiinositolphosphorylceramide and glucosylceramides, are selective binding sites for the plant defensins isol
Publicado em: 2006
-
7. Morphology of defensin-treated Staphylococcus aureus.
Defensins are a family of broad-spectrum antimicrobial peptides found abundantly in the cytoplasmic granules of mammalian neutrophils and Paneth cells of the small intestine. Defensins are known to form ion channels on the membranes of target cells. These channel formations and the cytotoxicity of defensins are intimately linked. We showed the morphological
-
8. Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes.
Human polymorphonuclear leukocytes (PMN) contain three antimicrobial and cytotoxic peptides which belong to a family of mammalian granulocyte peptides named defensins. To determine their potential availability for extracellular microbicidal or cytotoxic events, we quantified the extracellular release of defensins after stimulation of human PMN with phorbol m
-
9. Contribution of rabbit leukocyte defensins to the host response in experimental syphilis.
In the companion paper (L. A. Borenstein, M. E. Selsted, R. I. Lehrer, and J. N. Miller, Infect. Immun. 59:1359-1367, 1991), we report that rabbit alveolar macrophage and neutrophil derived defensins possess antimicrobial activity against Treponema pallidum subsp. pallidum, the etiologic agent of syphilis. In this study, antisera specific for NP-1 and NP-2 (
-
10. Isolation and Properties of Floral Defensins from Ornamental Tobacco and Petunia1
The flowers of the solanaceous plants ornamental tobacco (Nicotiana alata) and petunia (Petunia hybrida) produce high levels of defensins during the early stages of development. In contrast to the well-described seed defensins, these floral defensins are produced as precursors with C-terminal prodomains of 27 to 33 amino acids in addition to a typical secret
American Society of Plant Biologists.
-
11. Antibacterial Activity and Specificity of the Six Human α-Defensins
We developed a kinetic, 96-well turbidimetric procedure that is capable of testing the antimicrobial properties of six human α-defensins concurrently on a single microplate. The defensins were prepared by solid-phase peptide synthesis and tested against gram-positive bacteria (Staphylococcus aureus and Bacillus cereus) and gram-negative bacteria (Enterobact
American Society for Microbiology.
-
12. Expression of β-Defensin Genes in Bovine Alveolar Macrophages
Bovine alveolar macrophages (BAM) were examined for the expression of β-defensins and to determine whether their expression could be upregulated by bacterial lipopolysaccharide (LPS), as observed with β-defensins expressed in bovine tracheal epithelial cells. Four β-defensins were expressed constitutively in BAM, with bovine neutrophil β-defensin (BNBD)-
American Society for Microbiology.