Dectin 1
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Classical and alternative macrophages have impaired function during acute and chronic HIV-1 infection
Abstract Objectives: Three decades after HIV recognition and its association with AIDS development, many advances have emerged – especially related to prevention and treatment. Undoubtedly, the development of Highly Active Antiretroviral Therapy (HAART) dramatically changed the future of the syndrome that we know today. In the present study, we evaluate t
Braz J Infect Dis. Publicado em: 2017-02
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2. Novas funções da proteina AIRE : 1) seu papel na resposta mediada por dectina-1 em fagocitos mononucleares humanos. 2) sua associação com a queratina 17, proteina dos filamentos intermediarios / New roles of AIRE protein : 1) AIRE role in Dection-1 mediated patway in human mononuclear phagocytes and 2) AIRE association with keratin-17, a component of intermediate filaments
A Poliendocrinopatia autoimune associada a candidíase e distrofia ectodérmica (APECED) é um síndrome caracterizado pela presença de pelo menos dois sintomas clínicos, endocrinopatia autoimune, sendo que as mais comuns são hipoparatiroidismo, doença de Addison, além de candidíase mucocutânea crônica. É também comum nos pacientes o desenvolviment
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/07/2009
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3. Expressão de recptores do tipo Toll e dectina em monocitos e neutrofilos estimulados pelo Paracoccidioides brasiliensis / Expression of Toll-like receptos and dectin-1 in monocytes and neutrophils stimulated by Paracoccidioides brasiliensis
Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America caused by the dimorphic fungus Paracoccidioides brasiliensis. The pattern of the immune responses to P. brasiliensis determines the disease progression and clinical outcome. Innate immune response is mediated by phagocytic cells, such as macrophage and neutrophils, which ingest and kill inva
Publicado em: 2008
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4. Characterization of β-Glucan Recognition Site on C-Type Lectin, Dectin 1
Dectin 1 is a mammalian cell surface receptor for (1→3)-β-d-glucans. Since (1→3)-β-d-glucans are commonly present on fungal cell walls, it has been suggested that dectin 1 is important for recognizing fungal invasion. In this study we tried to deduce the amino acid residues in dectin 1 responsible for β-glucan recognition. HEK293 cells transfected wit
American Society for Microbiology.
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5. Activated Dectin-1 Localizes to Lipid Raft Microdomains for Signaling and Activation of Phagocytosis and Cytokine Production in Dendritic Cells*
Lipid rafts are plasma membrane microdomains that are enriched in cholesterol, glycosphingolipids, and glycosylphosphatidylinositol-anchored proteins and play an important role in the signaling of ITAM-bearing lymphocyte antigen receptors. Dectin-1 is a C-type lectin receptor (CLR) that recognizes β-glucan in the cell walls of fungi and triggers signal tran
American Society for Biochemistry and Molecular Biology.
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6. Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2
The discovery of several transmembrane receptors expressed by antigen presenting cells, including those that detect and interact with specific sugar moieties on the surface of microbes, has improved our understanding of how immunity against infection is generated. This knowledge, in turn, prompted us to review such interactions with emphasis on C-type lectin
Oxford University Press.
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7. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments
The ability of Candida albicans to rapidly and reversibly switch between yeast and filamentous morphologies is crucial to pathogenicity, and it is thought that the filamentous morphology provides some advantage during interaction with the mammalian immune system. Dectin-1 is a receptor that binds β-glucans and is important for macrophage phagocytosis of fun
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8. Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays
It is generally accepted that the glycans on the cell surface and extracellular matrix proteins play a pivotal role in the events that mediate re-epithelialization of wounds. Yet, the global alteration in the structure and composition of glycans, specifically occuring during corneal wound closure remains unknown. In this study, GLYCOv2 glycogene microarray t
Oxford University Press.