Cyclofuncionalization
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1. Design, synthesis and evaluation of biological derivatives pyrroles potentially antiinflamatory activity / Planejamento, síntese e avaliação biológica de derivados pirrólicos com potencial atividade antiinflamatória
The nonsteroidal antiinflammatory drugs (NSAIDs) are among the most prescribed and used drugs in the world. These drugs inhibit the cyclooxygenases, enzymes responsible for conversion of arachidonic acid into phlogistic prostaglandins, by the action of phospholipase A2. The synthesis of compounds containing pyrrole nucleus in their structures has been a topi
Publicado em: 2009