Cycle Slip
Mostrando 13-13 de 13 artigos, teses e dissertações.
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13. High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication.
Homo-oligomeric runs were inserted into a spleen necrosis virus-based retrovirus vector to determine the nature and rate of mutations within runs of 10 to 12 identical nucleotides during a single replication cycle. Clones of helper cells containing integrated copies of retroviral vectors were used to produce virus for infection of target (nonhelper) cells. P