Controlled Clinical Trials
Mostrando 1-12 de 339 artigos, teses e dissertações.
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1. Efficacy of opioids and non-opioid analgesics in the treatment of post procedure pain of burned patients: a narrative review
Abstract Introduction Burns are a common trauma that cause acute severe pain in up to 80% of patients. The objective of this narrative review is to evaluate the efficacy of opioids, non-steroidal anti-inflammatory drugs, paracetamol, gabapentinoids, ketamine, and lidocaine in the treatment of acute pain in burn victims. Methodology The databases explored w
Brazilian Journal of Anesthesiology. Publicado em: 2022
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2. Reperfusion Strategies in Acute Myocardial Infarction: State of the Art
Abstract ST elevation myocardial infarction (STEMI) is a highly prevalent condition worldwide. Reperfusion therapy is strongly associated with the prognosis of STEMI and must be performed with a high standard of quality and without delay. A systematic review of different reperfusion strategies for STEMI was conducted, including randomized controlled trials t
International Journal of Cardiovascular Sciences. Publicado em: 2022
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3. Melatonin use during pregnancy and lactation: A scoping review of human studies
Objective: The prevalence of sleep disorders during the perinatal period is high and large health administrative database surveys have shown that the use of exogenous melatonin in pregnant populations is quite common, about 4%. Much of the concern about using melatonin during pregnancy and breastfeeding stems from animal research. Thus, the objective of this
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Effect of Kangaroo Position on microcirculation of preterm newborns: a controlled randomized clinical trial
Abstract Objective: The objective of this study was to evaluate the effect of Kangaroo Position (KP) in microcirculation (MC) of the flexor muscles of preterm newborns. Method: A controlled clinical trial was conducted in the city of Recife, Brazil, with 26 preterm children randomized in the Kangaroo Group (13) and in the Control Group (13). Assessments of
Jornal de Pediatria. Publicado em: 2022
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5. Low-dose ketamine does not improve the speed of recovery from depression in electroconvulsive therapy: a randomized controlled trial
Objective: Electroconvulsive therapy (ECT) is a well-established therapeutic intervention for major depressive disorder. Recent literature has shown that the anesthetic agent ketamine has some antidepressant properties at low doses and may be an alternative therapy for treatment-resistant major depressive disorder. We hypothesized that the use of low-dose ke
Brazilian Journal of Psychiatry. Publicado em: 2022
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6. A narrative review on invasive brain stimulation for treatment-resistant depression
While most patients with depression respond to pharmacotherapy and psychotherapy, about one-third will present treatment resistance to these interventions. For patients with treatment-resistant depression (TRD), invasive neurostimulation therapies such as vagus nerve stimulation, deep brain stimulation, and epidural cortical stimulation may be considered. We
Brazilian Journal of Psychiatry. Publicado em: 2022
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7. Acceptance of Low-Sodium Hospital Diet by Cardiac Patients: A Randomized Controlled Crossover Trial
Abstract Background Cardiovascular diseases are the major cause of hospitalization. Dietary salt restriction is indicated as part of clinical treatment, however, it is not always well accepted by the patients, resulting in low food intake and malnutrition. Objective To compare acceptance of a low-sodium diet cooked with salt with a standard low-sodium di
International Journal of Cardiovascular Sciences. Publicado em: 2022
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8. Augmented reality in interventional radiology education: a systematic review of randomized controlled trials
ABSTRACT BACKGROUND: Augmented reality (AR) involves digitally overlapping virtual objects onto physical objects in real space so that individuals can interact with both at the same time. AR in medical education seeks to reduce surgical complications through high-quality education. There is uncertainty in the use of AR as a learning tool for interventional
Sao Paulo Medical Journal. Publicado em: 2022
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9. Inferior Turbinate Reduction during Rhinoplasty: Is There Any Effect on Rhinitis Symptoms?
Abstract Introduction Inferior turbinate surgery is often performed concomitantly with rhinoseptoplasty. As inferior turbinates play a major role in allergic rhinitis, it seems reasonable to suggest that inferior turbinate surgery reduces allergy. Objective To assess the impact of nasal turbinate surgery on non-obstructive allergic symptoms (nasal discharg
International Archives of Otorhinolaryngology. Publicado em: 2022
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10. Meta-Analysis of Pulmonary Artery Denervation for Treatment of Pulmonary Hypertension
ABSTRACT Introduction: Pulmonary artery denervation (PADN) can reduce the sympathetic nervous system (SNS) activity, reduce pulmonary artery pressure (PAP), and improve the quality of life in patients with pulmonary hypertension (PH). We conducted a systematic meta-analysis of the effectiveness of PADN in the treatment of PH patients. Methods: This is a co
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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11. Effect of Physical Training on Nitric Oxide Levels in Patients with Arterial Hypertension: An Integrative Review
Abstract The regular practice of physical exercise as a non-pharmacological treatment of arterial hypertension (AH) has been encouraged due to causing a series of physiological responses in the cardiovascular system, such as the production of vasoactive substances, including nitric oxide (NO). NO is a relaxation factor released by the endothelium, and the de
International Journal of Cardiovascular Sciences. Publicado em: 2022
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12. Efficacy and safety of dexmedetomidine in maintaining hemodynamic stability in pediatric cardiac surgery: a systematic review and meta-analysis
Abstract Objectives: Dexmedetomidine (DEX) is a highly selective alpha-2 adrenergic receptor agonist, which is the main sedative in the intensive care unit. This study aims to investigate the effectiveness and adverse events of DEX in maintaining hemodynamic stability in pediatric cardiac surgery. Sources: Databases such as PubMed, Cochrane, Web of Science,
Jornal de Pediatria. Publicado em: 2022