Coli Forms
Mostrando 13-24 de 1221 artigos, teses e dissertações.
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13. Caracterização bioquímica de uma Leucil-aminopeptidase de Trypanosoma cruzi (LAPTc)
Pathogens depend on peptidase activities to accomplish many physiological processes, as well as to interact with their hosts, highlighting parasitic peptidases as virulence factors and, thus, potential drug targets. The kinetoplastid Trypanosoma cruzi genome sequencing, the aetiological agent of Chagas disease, has revealed 28 genes encoding putative aminope
Publicado em: 2010
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14. Desenvolvimento analítico e farmacotécnico de formas farmacêuticas sólidas de isoflavona de soja / Pharmaceutics and analytical development of solid dosage forms of soy isoflavones
Isoflavonas são flavonóides encontrados em abundância nos grãos de soja (Glycine max L.). Essas substâncias têm estrutura semelhante ao estrógeno e possuem uma ação fracamente estrogênica. São utilizadas no tratamento dos sintomas da menopausa como alternativa às terapias de reposição hormonal convencionais, por provocarem menor número de efei
Publicado em: 2010
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15. Potencial probiÃtico de lactobacilos de origem suÃna / Potentially probiotic lactobacilli of porcine origin
The use of probiotic in animal nutrition has been identified for reducing mortality resulting from intestinal colonization by pathogenic micro-organisms, improving the performance and characteristics of production, leaving no residue in meat. The experiment aimed to isolate, from faeces samples from swine in the suckling strains of lactobacilli in order to b
Publicado em: 2009
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16. Padronização da expressão heterologa e de modelo de ensaio de atividade para a proteina quinase humana S6K / Standardization of the heterologous expression and of a model assay of activity for the human protein kinase S6K
The 70kDa ribosomal S6 protein kinase 1 (S6K1) is a phosphoprotein involved in the regulation of genes related to translational control in mammals. S6K1 shows distinct nuclear (a1) and cytoplasmic (a2) forms. Phosphorylation of the S6K1 best characterized target, the protein of the small ribosomal subunit (RPS6), has been generally associated to the selectiv
Publicado em: 2009
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17. Characterization of genes of unknown function with expression linked to the infective forms of Trypanosoma Cruzi / Caracterização de Genes de Função Desconhecida com Expressão Associada às Formas Infectivas do Trypanosoma cruzi
Atualmente novas abordagens e metodologias de pesquisa nos permitem iniciar projetos de caracterização de um conjunto de proteínas de um determinado organismo em escalas superiores aos realizados há algum tempo. Novas tecnologias para seqüenciamento, clonagem e expressão protéica permitem a geração de uma quantidade grande de novas informações num
Publicado em: 2009
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18. AnÃlise da antigenicidade e expressÃo de quatro novas proteÃnas hipotÃticas de Leishmania.(Leishmania) Chagasi
Leishmaniasis are parasitary infectious-diseases endemic in many countries caused by protozoan parasites of the genus Leishmania. Current strategies to combat visceral leishmaniasis, the most lethal and often fatal form of the disease unless treated, have not so far been successful. For this reason identification of recombinant antigens that can be used in d
Publicado em: 2009
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19. Estuário do rio Acaraú: Impactos ambientais e implicações na qualidade dos recursos hídricos. / Acaraú River Estuary: Environmental impacts and implications for the quality of water resources.
Estuaries are environments of transition between the continents and the oceans. They shelter great diversity of aquatic fauna and significant mangrove ecosystem. However they are especially frail environments, being more vulnerable than other environments In this sense, the place of this research is the region that encloses Acarau river estuary and its outsk
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/04/2008
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20. Development of a new vaccine approach against hemolytic uremic syndrome using genetically modified Bacillus subtilis strain expressing Stx2 EHEC toxin. / Desenvolvimento de uma nova estratégia vacinal contra síndrome hemolítica urêmica utilizando linhagens geneticamente modificadas de Bacillus subtilis capazes de expressar a toxina Stx2 de EHEC.
The Hemolytic Uremic Syndrome (HUS) is the main disease associated with infections with Shiga toxin (Stx) - producing Escherichia coli strain and no effective vaccine or treatment exist. The Stx toxin consist of an enzymatically active A subunit and a pentameric B subunit responsible toxin binding to host cells. In this work we propose the use of Bacillus su
Publicado em: 2008
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21. Evaluation of aquose extracts of plants in the treatment of mares infections endometrites (Equus caballus). / Avaliação de Extratos Aquosos de Plantas no Tratamento da Endometrite Bacteriana em Éguas (Equus caballus).
This study was conducted during 2005-2007 seasons, and aimed at the evaluation of the activity of extracts of plants in isolated bacteria from susceptible uterus of mares. Twenty-one susceptible to endometritis animals were selected after a gynecological exam performed in 135 mares located in private properties and Instituto de Zootecnia from UFRRJ. Uterine
Publicado em: 2008
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22. Estudos moleculares das enzimas envolvidas na biossíntese de selenocisteína em Trypanosoma brucei e Leishmania major / Molecular studies of the enzymes involved in selenocysteine synthesis in Trypanosoma brucei and Leishmania major
One of the main biological forms of the selenium incorporation is the amino acid form named selenocysteine (Sec, U), which is incorporated co-translationally at the emerging new polypeptide in the specific positions at the UGA codon, that is usually recognized as stop codon. The incorporation of the selenocysteine in E.coli is already solved with the involve
Publicado em: 2008
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23. Estudos estruturais do domínio catalítico da proteína tirosina fosfatase eta de rato / Structural studies of the catalytic domain of the rat protein tyrosine phosphatase eta
The rat protein tyrosine phosphatase eta, rPTPeta, is a transmembrane RPTP, with an intracellular portion composed of a unique catalytic region. The rPTPeta and the human homolog DEP-1 are down-regulated in rat and human neoplastic cells, respectively. However, the malignant phenotype is reverted after exogenous reconstitution of rPTPeta, suggesting that its
Publicado em: 2008
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24. Estudos estruturais de histatina-5 e seu análogo, TOAC0-histatina-5: interação com metais e sistemas biomiméticos / Structural studies of Histatin-5 and its analogue, TOAC0-Histatin-5: interaction with metals and biomimetic systems
The mechanism of action of histatin-5 (Hst-5), an antifungal antimicrobial peptide from human saliva is not completely clarified. Circular dichroism (CD), fluorescence, and electron paramagnetic resonance (EPR) were used to examine the conformational behavior of Hst-5 and its analogue containing the paramagnetic amino acid TOAC at the N-terminus (TOAC0-Hst-5
Publicado em: 2008