Claisen Schmidt Condensation
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Design, Synthesis and Antitubercular Activity of Novel Isoniazid-Cyclic-Amine-Azachalcones Hybrids
In this work, it is described the design of twenty-four heterocyclic amine-azachalcones compounds through molecular hybridization of chalcone scaffold and fragments of isoniazid, fluoroquinolones, and linezolid with antituberculosis potential. The new compounds were synthesized via Claisen-Schmidt condensation, providing yields of 36-95%. Fifteen compounds s
J. Braz. Chem. Soc.. Publicado em: 2020-06
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2. Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones
It was synthesized nine polyoxygenated chalcones with a potential and safe use as antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen-Schmidt condensation were studied as antioxidant, inhibitors of human 5-lipoxygenase, antifungal, antibacterial and antibiotic resistance modifiers. Two chalcones with catecholic moieties
J. Braz. Chem. Soc.. Publicado em: 2019-02
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3. ALÉM DA CAIPIRINHA: CACHAÇA COMO SOLVENTE PARA SÍNTESE ORGÂNICA E EXTRAÇÃO DE PIGMENTO
Cachaça (brazilian sugarcane spirit) was applied for the first time as an alternative solvent in undergraduate experiments of organics synthesis, and natural dye extraction. The classical Claisen-Schmidt condensation of benzaldehyde with acetophenone and with acetone were employed to demonstrate the cachaça viability as solvent. Cachaça was also the recry
Quím. Nova. Publicado em: 2017-10
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4. Conformational Variability in Sulfonamide Chalcone Hybrids: Crystal Structure and Cytotoxicity
Four sulfonamide-chalcone derivatives were prepared and their crystal structure were elucidated by single-crystal X-ray diffraction technique. They were synthesized by Claisen-Schmidt condensation reaction between N-(4-acetylphenyl)benzenesulfonamide or N-(4-acetylphenyl)-2,5-dichlorobenzenesulfonamide with benzaldehyde or p-nitrobenzaldehyde. Values of Z' >
J. Braz. Chem. Soc.. Publicado em: 2016-05
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5. Planejamento racional no desenvolvimento de novos derivados de Chalcona como agentes anti-Candida albicans / Rational planning in the development of new Chalcone derivatives as anti-Candida albicans
O objetivo do presente trabalho foi identificar os principais descritores dos derivados análogos de chalcona com intuito de correlacionar com a atividade anti-Candida albicans. A incidência de infecções sistêmicas por C. albicans vem crescendo bastante nos últimos anos, particularmente nos casos de HIV e também em função do aumento da resistência a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/01/2012
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6. Aplicação de peneiras moleculares contendo cátions orgânicos em catálise básica
This thesis was aimed at studying novel basic catalysts based on molecular sieves containing alkylammonium cations. The studied molecular sieves were faujasite zeolites (FAU) and mesoporous silicate (like MCM-41). The following parameters were evaluated: (1) different alkylammonium cations, (2) different amount of alkylammonium cations and (3) application of
Publicado em: 2008