Chlorpromazine
Mostrando 1-12 de 158 artigos, teses e dissertações.
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1. Behavioral effects of Bj-PRO-7a, a proline-rich oligopeptide from Bothrops jararaca venom
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic receptors subtype 1 (M1R). However, whether Bj-PRO-7a acts upon the central nervous system and modifies b
Braz J Med Biol Res. Publicado em: 07/11/2019
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2. Influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury
ABSTRACT PURPOSE: To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. METHODS: Sixteen Wistar rats - split in two groups - have been used: control group, receiving 3 mg/kg isotonic saline solution through caudal vein, and, the chlorpromazine group, receiving 3 mg/kg-IV of such medication. The
Acta Cir. Bras.. Publicado em: 2016-11
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3. Regulatory volume decrease in Leishmania mexicana: effect of anti-microtubule drugs
The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume decrease (RVD). We studied the effects of
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-02
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4. Participação dos canais de potássio no efeito relaxante do ácido ent-7a-hidroxitraquiloban-18-oico em traqueia isolada de cobaia / Participation of potassium channels in the ent-7a-hidroxitrachyloban-18-oic acid relaxation effect on guinea pig trachea
From Xylopia langsdorfiana A. St-Hil. &Tul. stem bark was isolated the diterpene of trachylobane class, ent-7α-hydroxytrachyloban-18-oic acid (trachylobane-318) that in previous studies showed to be able to relax guinea-pig trachea pre-contracted by carbachol (CCh). Thus, we aimed to investigate the action mechanism underlying in this trachylobane-318 r
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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5. Psychosocial interventions for premature ejaculation
BACKGROUND: Premature ejaculation (PE) is a very common sexual dysfunction among patients, and with varying prevalence estimates ranging from 3% to 20%. Although psychological issues are present in most patients with premature PE, as a cause or as a consequence, research on the effects of psychological approaches for PE has in general not been controlled or
Sao Paulo Medical Journal. Publicado em: 2012
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6. Efeitos neurocomportamentais e neuroquÃmicos da clorpromazina e clozapina no modelo de esquizofrenia induzido pela cetamina em camundongos. / Neurobehavioral and neurochemical effects of chlorpromazine and clozapine in the model of schizophrenia induced by ketamine in mice.
A esquizofrenia à um transtorno mental crÃnico, grave e incapacitante que afeta cerca de 1% da populaÃÃo mundial, cujos sintomas podem ser induzidos pela Cetamina. Neste sentido, hà evidÃncias de que o estresse oxidativo tenha importante papel na patogÃnese desta doenÃa. Desta forma, o presente estudo avaliou os efeitos neurocomportamentais e neuroqu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/05/2011
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7. FOTODEGRADATION OF PHENOTHIAZINES AND THEIR STRUCTURAL EFFECTS ON NA(+)K(+) - ATPASE: A FLUORESCENCE STUDY / FOTODEGRADAÇÃO DE FENOTIAZINAS E SEUS EFEITOS ESTRUTURAIS SOBRE A NA(+), K(+) - ATPASE: ESTUDO ATRAVÉS DE FLUORESCÊNCIA
Chlorpromazine (CPZ), fluphenazine (FPZ) and trifluoperazine (TFP) are phenothiazine derivatives, which generate photoproducts under UV irradiation. We observed that CPZ develops three fluorescent fotoproducts under different conditions. Promazine (PZ) that forms from the CPZ photolysis. The chlorine loss is one of the main pathways for photoproduct formatio
Publicado em: 2010
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8. Avaliação de seis protocolos pré-anestésicos para anestesia epidural de caninos / Evaluation of six pre-anesthetic combinations to canine epidural anesthesia
Vários protocolos de pré-anestesia podem ser usados em esquemas de anestesia que incluam anestesia epidural. A disponibilidade de diferentes fármacos e combinações permite a escolha de um procedimento anestésico específico para cada paciente, dependendo do grau de risco anestésico e do temperamento do animal. A escolha do protocolo pré anestésico d
Publicado em: 2010
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9. AÇÃO DA CLORPROMAZINA EM RINS DE CÃES SUBMETIDOS À ISQUEMIA E REPERFUSÃO / ACTION chlorpromazine in KIDNEYS OF DOGS SUBMITTED TO ISCHEMIA AND REPERFUSION
Renal ischemia is present in different situations such as vascular or kidney surgery and also in renal transplantation. The aim of this study was to evaluate the renal function in dogs submitted to ischemia and reperfusion after chlorpromazine application. Twelve adult mongrel dogs were distributed into two groups with six animals: group A - ischemia and rep
Publicado em: 2009
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10. ACTION chlorpromazine in KIDNEYS OF DOGS SUBMITTED TO ISCHEMIA AND REPERFUSION / AÇÃO DA CLORPROMAZINA EM RINS DE CÃES SUBMETIDOS À ISQUEMIA E REPERFUSÃO
O objetivo deste trabalho foi avaliar a função renal e a expressão da E-caderina e -catenina de cães submetidos à isquemia e reperfusão após a aplicação de clorpromazina. Para tais objetivos, foram utilizados 12 cães distribuídos aleatoriamente em dois grupos de seis indivíduos: grupo A com isquemia e reperfusão sem tratamento por clorpr
Publicado em: 2009
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11. EFFECTS OF AN ANTIPSYCHOTIC AND A TRICYCLIC ANTIDEPRESSANT ON THE SODIUM AND POTASSIUM PUMP NA+,K+ -ATPASE: A FLUORESCENCE STUDY / EFEITOS DE UM ANTIPSICÓTICO E UM ANTIDEPRESSIVO TRICÍCLICO SOBRE A BOMBA DE SÓDIO E POTÁSSIO, NA+,K+-ATPASE: ESTUDO ATRAVÉS DE FLUORESCÊNCIA
A bomba de sódio e potássio Na+,K+-ATPase é uma enzima que oscila entre duas conformações principais E1 e E2 durante o ciclo de transporte dos íons Na+ e K+ através de membranas. O esteróide cardiotônico ouabaína é um inibidor específico que se liga à enzima na conformação E2. A sonda fluorescente antroilouabaína (AO) apresenta incremento de
Publicado em: 2005
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12. Quenching of the intrinsic fluorescence of bovine serum albumin by chlorpromazine and hemin
The binding of chlorpromazine (CPZ) and hemin to bovine serum albumin was studied by the fluorescence quenching technique. CPZ is a widely used anti-psychotic drug that interacts with blood components, influences bioavailability, and affects function of several biomolecules. Hemin is an important ferric residue of hemoglobin that binds within the hydrophobic
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-07