Ceruloplasmin
Mostrando 13-24 de 99 artigos, teses e dissertações.
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13. Alterações plasmáticas do cobre e do zinco em crianças submetidas a cirurgia cardíaca com circulação extracorpórea
The cardiac surgery, comprising extracorporeal circulation, is known to trigger oxidative stress due to the formation of reactive oxygen species and free radicals during the periods of ischemia and reperfusion. They are hazardous to the heart cell components and regarded as responsible for the myocardial stunned. These processes are intricately associated wi
Publicado em: 2008
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14. Influência do puerpério e da retenção dos anexos fetais no proteinograma de fêmeas bovinas da raça Holandesa, criadas no Estado de São Paulo / Influence of puerperium and retained fetal membranes on the proteinogram of Holstein cows raised in the State of São Paulo
The aim of this study was to evaluate the influence of the puerperal period and retained fetal membranes on the proteinogram of Holstein cows. Two hundred ninety one blood samples were collected from cows through ninety days postpartum. In order to study the physiologic puerperium, blood samples from one hundred two clinically animals, divided in 9 experimen
Publicado em: 2008
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15. Cupriuresis in parents of patients with Wilson disease before and after oral intake of d-penicillamine / Cuprúria em pais de pacientes com doença de Wilson antes e depois da administração oral de d-penicilamina
Wilson disease is a biliary copper excretion disturbance, of recessive autossomic heritage, due to ATP7B gene mutations. The copper not bound to apoceruloplasmin circulates in the organism bound to amino acids and accumulates mainly in the liver and brain being excreted by the kidneys. Urinary copper higher than 100ug/24h can be useful in the diagnosis, but
Publicado em: 2007
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16. Proteinograma sérico de bezerros recém-nascidos da raça Holandesa obtido por eletroforese em gel de poliacrilamida
The serum protein concentration of newborn Holstein calves determined by means of sodium dodecyl sulphate-polyacrylamide (SDS-PAGE) was studied. Blood samples from 40 healthy newborn calves were obtained 48 hours after birth. Calves had been given 3 liters of colostrum within 2 hours after birth, following by dose corresponding by 15% of animal weight each 2
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2006-06
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17. Análise de biomarcadores de balanço redox em portadores de hipertensão arterial primária: uma avaliação segundo técnicas bioquímicas, cromatográficas e espectrofotométricas. / Analysis of redox imbalance biomarkers in hypertenses: evaluation based upon biochemical, chromatographic and spectrophotometric techniques.
The participation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in systemic arterial hypertension (SAH) has been described in recent papers, which indicate the importance of studying the phenomena that influences the redox environment in blood of patients with high blood pressure (hypertenses), as well as the dietary aspects that could
Publicado em: 2006
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18. Ceruloplasmin in Wilson's Disease*
Ceruloplasmin was highly purified from one patient with Wilson's disease and partially purified from a second unrelated patient. The highly purified ceruloplasmin was indistinguishable from normal ceruloplasmin by electrophoresis, tryptic peptide map, oxidase activity, and copper, amino acid, and sugar composition. The partially purified ceruloplasmin was in
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19. Role of endogenous ceruloplasmin in low density lipoprotein oxidation by human U937 monocytic cells.
Oxidation of lipids and lipoproteins by macrophages is an important event during atherogenesis. Activation of monocytic cells by zymosan and other agonists results in the release of multiple oxidant species and consequent oxidation of LDL. We now show evidence that ceruloplasmin, a copper-containing acute phase reactant, is secreted by zymosan-activated U937
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20. The role of ceruloplasmin in iron metabolism
The importance of ceruloplasmin in iron metabolism was studied in swine made hypoceruloplasminemic by copper deprivation. When the plasma ceruloplasmin level fell below 1% of normal, cell-to-plasma iron flow became sufficiently impaired to cause hypoferremia, even though total body iron stores were normal. When ceruloplasmin was administered to such animals,
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21. Intact human ceruloplasmin oxidatively modifies low density lipoprotein.
Ceruloplasmin is a plasma protein that carries most of the copper found in the blood. Although its elevation after inflammation and trauma has led to its classification as an acute phase protein, its physiological role is uncertain. A frequently reported activity of ceruloplasmin is its ability to suppress oxidation of lipids. In light of the intense recent
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22. Molecular studies of ceruloplasmin deficiency in Wilson's disease.
Deficiency of serum ceruloplasmin is a characteristic biochemical abnormality of Wilson's disease, although the mechanism of this finding is unknown. Ceruloplasmin messenger RNA (mRNA) levels were therefore examined in five patients with Wilson's disease and five controls with other types of hepatic disease. Northern and dot blot hybridizations showed that d
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23. Ceruloplasmin and regulation of transferrin iron during Neisseria meningitidis infection in mice.
The role of ceruloplasmin (ferroxidase I; EC 1.16.3.1) in iron metabolism during experimental Neisseria meningitidis infection was investigated. Plasma ceruloplasmin activity was found to increase greatly in mice during the convalescence phase of iron-controlled infection and after a plasma hypoferremia had occurred. Ceruloplasmin activity-deficient animals
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24. Measurement of Gastrointestinal Protein Loss Using Ceruloplasmin Labeled with 67Copper*
Ceruloplasmin labeled with 67copper and administered intravenously to dogs, control human subjects, and patients with excessive gastrointestinal loss was shown to fulfill the requirements for a label for quantification of gastrointestinal protein loss. The radiocopper moiety was poorly absorbed from the gastrointestinal tract, not actively secreted into the