Cellular Differentiation
Mostrando 13-24 de 1472 artigos, teses e dissertações.
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13. Deferoxamine synergizes with transforming growth factor-β signaling in chondrogenesis
Abstract Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, is an epidemic disease that affects millions of people worldwide. Despite extensive recent work on the cellular biology of osteoarthritis, the precise mechanisms involved are still poorly understood and there is no effective treatment for this disease. The role of tr
Genet. Mol. Biol.. Publicado em: 14/08/2017
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14. Development of VEGF-loaded PLGA matrices in association with mesenchymal stem cells for tissue engineering
The association of bioactive molecules, such as vascular endothelial growth factor (VEGF), with nanofibers facilitates their controlled release, which could contribute to cellular migration and differentiation in tissue regeneration. In this research, the influence of their incorporation on a polylactic-co-glycolic acid (PLGA) scaffold produced by electrospi
Braz J Med Biol Res. Publicado em: 07/08/2017
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15. Molecular biology of human epidermal receptors, signaling pathways and targeted therapy against cancers: new evidences and old challenges
ABSTRACT Human epidermal receptors (HER1/2/3/4) belong to the class of receptor-type tyrosine kinases. After binding a ligand, dimerization, it will ocurr activation of intracellular kinases after two-dimensional and cytoplasmic tail reciprocal transphosphorylation. This transphosphorylation recruits signaling pathways such as Ras/Raf/MEK/Erk1-2, PI3-K/AKT a
Braz. J. Pharm. Sci.. Publicado em: 20/07/2017
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16. Preparation, Characterization and Biological Studies of Β-TCP and Β-TCP/Al2O3 Scaffolds Obtained by Gel-Casting of Foams
Replacement tissues for tissue engineering can be produced by seeding human cells onto scaffolds. In order to guarantee adequate bio-compatibility, porosity and mechanical resistance for promoting cellular growth, proliferation and differentiation within scaffold structures, it is necessary to investigate and improve materials and processing routes. β-trica
Mat. Res.. Publicado em: 22/05/2017
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17. Development of carpels and ovules in Dialypetalanthus fuscescens Kuhlm. (Rubiaceae): an enigmatic taxon
ABSTRACT Dialypetalanthus is a monospecific genus that occurs in the Amazon Basin of Brazil, Bolivia and Peru and occupies a controversial position among the Rubiaceae. We continue this taxonomic discussion with the overall aim of clarifying the systematic position of D. fuscescens within the Rubiaceae. To accomplish this, we analyzed the ontogeny of its gyn
Acta Bot. Bras.. Publicado em: 2017-03
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18. Detection value of free cancer cells in peritoneal washing in gastric cancer: a systematic review and meta-analysis
Intraperitoneal free cancer cells in gastric adenocarcinoma are associated with a poor outcome. However, the true prognostic value of intraperitoneal free cancer cells is still unclear, leading to a lack of consensus in the management of gastric cancer. The aim of the present study is to perform a systematic review and meta-analysis to analyze intraperitonea
Clinics. Publicado em: 2016-12
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19. Rat dental pulp stem cells: isolation and phenotypic characterization method aiming bone tissue bioengineering
ABSTRACT: Dental pulp stem cells (DPSC) have been showing a considerable potential for regenerative medicine. Pulps were collected from lower incisors (n=2) through direct access of the tooth pulp chamber. The isolated cells were cultured in alfa-MEM 10% FBS, in standard culture conditions. At the third passage, DPSC were characterized by flow cytometry (MHC
Braz. arch. biol. technol.. Publicado em: 27/06/2016
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20. Genes Regulating Maternal Recognition of Pregnancy in Domestic Animals: an Update
ABSTRACT Early embryonic mortality is one of the main sources of reproductive wastages and major constraints for full exploitation of the production potential of livestock. The survivality of embryo during early embryonic life is mostly dependent on the efficiency with which the maternal recognition of pregnancy (MRP) is established. Maternal recognition of
Braz. arch. biol. technol.. Publicado em: 2015-12
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21. Expression of annexin A1 in Leishmania-infected skin and its correlation with histopathological features
ABSTRACTINTRODUCTION:The aim of this study was quantify annexin A1 expression in macrophages and cluster of differentiation 4 (CD4) + and cluster of differentiation 8 (CD8)+ T cells from the skin of patients with cutaneous leishmaniasis (n=55) and correlate with histopathological aspects.METHODS:Infecting species were identified by polymerase chain reaction-
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-10
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22. Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma
AbstractNeurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurothekeoma and nerve sheath myxoma. Herein we describe a 19-year-old
An. Bras. Dermatol.. Publicado em: 2015-06
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23. Isolamento, expansão e diferenciação de progenitors celulares obtidos da polpa dentária de cutia (Dasyprocta prymnolopha Wagler, 1831)
Resumo: Isolation, expansion and differentiation of cellular progenitors obtained from dental pulp of agouti (Dasyprocta prymnolopha Wagler, 1831). Este estudo teve como objetivo isolar, expandir, diferenciar e caracterizar células progenitoras existentes na polpa dentária de cutia. O material foi lavado em solução de PBS e dissociado mecanicamente, com
Pesq. Vet. Bras.. Publicado em: 2015-06
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24. Brazilian minipig as a large-animal model for basic research and stem cell-based tissue engineering. Characterization and in vitro differentiation of bone marrow-derived mesenchymal stem cells
Stem cell-based regenerative medicine is one of the most intensively researched medical issues. Pre-clinical studies in a large-animal model, especially in swine or miniature pigs, are highly relevant to human applications. Mesenchymal stem cells (MSCs) have been isolated and expanded from different sources. Objective: This study aimed at isolating and char
J. Appl. Oral Sci.. Publicado em: 2014-06