Ccd Experimental Design
Mostrando 1-12 de 19 artigos, teses e dissertações.
-
1. PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger
This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3 variables (temperature, mass of native A. niger lipase and
Química Nova. Publicado em: 2022
-
2. Application of quality by design approach in RP-HPLC method development for simultaneous estimation of saxagliptin and dapagliflozin in tablet dosage form
A simple, sensitive, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of saxagliptin (SAXA) and dapagliflozin (DAPA) in pharmaceutical formulation. Design of experiments (DoE) was applied for multivariate optimization of the experimental conditions of RP-HPLC method. Risk assessment wa
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
-
3. APPLICATION OF RESPONSE SURFACE METHODOLOGY FOR LIPASE CATALYZED SYNTHESIS OF 2-ETHYLHEXYL PALMITATE IN A SOLVENT FREE SYSTEM USING ULTRASOUND
Abstract This study aims at clean production of 2-ethylhexyl palmitate catalyzed by lipase Fermase CALB 10000 in a solvent-free system using ultrasound technology. The central composite design (CCD) of response surface methodology with 4 factors at 3 levels consisting of acid to alcohol molar ratio (1:3-1:7), enzyme loading (3 %-7% (w/w)), ultrasound power (
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
-
4. Optimizing culture conditions for production of intra and extracellular inulinase and invertase from Aspergillus niger ATCC 20611 by response surface methodology (RSM)
Abstract The aim of this study was obtain a model that maximizes growth and production of inulinase and invertase by Aspergillus niger ATCC 20611, employing response surface methodology (RSM). The RSM with a five-variable and three-level central composite design (CCD) was employed to optimize the medium composition. Results showed that the experimental data
Braz. J. Microbiol.. Publicado em: 2017-07
-
5. Application of Response Surface Methodology for Optimizing Process Parameters in the Production of Amylase by Aspergillus flavusNSH9 under Solid State Fermentation
Amylase is recognized as one of the important commercial enzymes. This group of enzymes has the ability in hydrolyzing starch into smaller oligosacharides. The present work aimed to determine the optimum fermentation conditions for maximum production of crude amylase enzyme by Aspergillus flavus NSH9 employing response surface methodology (RSM).Central compo
Braz. arch. biol. technol.. Publicado em: 06/05/2016
-
6. PREDICTION OF STABILITY AND THERMAL CONDUCTIVITY OF SnO2NANOFLUID VIA STATISTICAL METHOD AND AN ARTIFICIAL NEURAL NETWORK
Abstract Central composite rotatable design (CCRD) and artificial neural networks (ANN) have been applied to optimize the performance of nanofluid systems. In this regard, the performance was evaluated by measuring the stability and thermal conductivity ratio based on the critical independent variables such as temperature, particle volume fraction and the pH
Braz. J. Chem. Eng.. Publicado em: 2015-12
-
7. OPTIMIZATION OF THE OPERATING CONDITIONS FOR RHAMNOLIPID PRODUCTION USING SLAUGHTERHOUSE-GENERATED INDUSTRIAL FLOAT AS SUBSTRATE
AbstractBiosurfactants have a wide range of applications in emulsions, separations, and solubilization because these chemicals reduce the surface tension and viscosity of solutions. This work studied rhamnolipid production using a batch bioreactor with a working volume of 1.5 liters, Pseudomonas aeruginosa ATCC (American Type Culture Collection) 10145 strain
Braz. J. Chem. Eng.. Publicado em: 2015-06
-
8. Use of multivariate experimental designs for optimizing the reductive degradation of an azo dye in the presence of redox mediators
The optimization of the anaerobic degradation of the azo dye Remazol golden yellow RNL was performed according to multivariate experimental designs: a 2² full-factorial design and a central composite design (CCD). The CCD revealed that the best incubation conditions (90% color removal) for the degradation of the azo dye (50 mg L- 1) were achieved with 350 m
Quím. Nova. Publicado em: 2014-06
-
9. Optimization of zofimarin production by an endophytic fungus, Xylaria sp. Acra L38
To optimize the medium for high zofimarin production, sucrose maltose, glucose, tryptone and peptone were used in an orthogonal array design experiment, where the highest value of zofimarin produced was 25.6 µg/mL. This value was about 3 times higher than that obtained with Czapek yeast extract (CzYE) culture medium. A study with Plackett-Burman design show
Braz. J. Microbiol.. Publicado em: 2014
-
10. Degradation of the herbicide paraquat by photo-fenton process: optimization by experimental design and toxicity assessment
Este trabalho descreve a influência e otimização dos reagentes de Fenton (concentração de Fe2+ e H2O2) na eficiência da mineralização do herbicida paraquat (PQT, 50 mg L-1) em água, após 60 min (equivalendo a 642 kJ L-1 de radiação UVA acumulada) de tratamento por processo foto-Fenton em escala de laboratório, usando planejamento composto centra
J. Braz. Chem. Soc.. Publicado em: 2013-01
-
11. Statistical evaluation of nutritional components impacting phycocyanin production in Synechocystis SP
Alkaliphilic cyanobacterial cultures were isolated from Lonar lake (MS, India). Among the set of cultures, Synechocystis sp, was studied for phycocyanin production. A maximum yield was obtained in BG-11 medium at optimized conditions (pH 10 and 16 h light). In order to increase the phycocyanin yield media optimization based on the eight media components a Pl
Brazilian Journal of Microbiology. Publicado em: 2012-03
-
12. Statistical optimisation of cell growth and carotenoid production by Rhodotorula mucilaginosa
Sequential statistical methods were used to maximise carotenoid production by a strain of Rhodotorula mucilaginosa, isolated from the Brazilian ecosystem. Initially, a factorial 2(5-1) experimental design was used, and the variables were pH and the levels of glucose, yeast extract, MgSO4.7H2O and KH2PO4. The nitrogen source (yeast extract) was the most impor
Brazilian Journal of Microbiology. Publicado em: 2012-03