Cargo Transportation
Mostrando 25-26 de 26 artigos, teses e dissertações.
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25. Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor
Clathrin-coated pits at the cell surface select material for transportation into the cell interior. A major mode of cargo selection at the bud site is via the µ2 subunit of the AP-2 adaptor complex, which recognizes tyrosine-based internalization signals. Other internalization motifs and signals, including phosphorylation and ubiquitylation, also tag certai
Oxford University Press.
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26. Myo6 Facilitates the Translocation of Endocytic Vesicles from Cell Peripheries
Immunolocalization studies in epithelial cells revealed myo6 was associated with peripherally located vesicles that contained the transferrin receptor. Pulse-chase experiments after transferrin uptake showed that these vesicles were newly uncoated endocytic vesicles and that myo6 was recruited to these vesicles immediately after uncoating. GIPC, a putati
The American Society for Cell Biology.