Carcinoma Renal Cells
Mostrando 1-12 de 79 artigos, teses e dissertações.
-
1. Immunohistochemical expressionof sodium-dependent glucose transporter - 2 (SGLT-2) in clear cell renal carcinoma: possible prognostic implications
ABSTRACT Purpose: Glucose is a major energy resource for tumor cell survival and growth, and its influx into cells is mainly carried out by facilitative glucose transporters (GLUTs). Sodium - dependent glucose transporters (SGLTs) have been highlighted as playing important roles in diabetic treatment. However, their potential roles in cancer remain unclear.
Int. braz j urol.. Publicado em: 2019-01
-
2. Association of primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with clear cell renal carcinoma
Hypercalcemia is found frequently in patients with cancer. Besides the etiology related to the malignancy, other causes should be considered in the differential diagnostic, as primary hyperparathyroidism, granulomatous diseases and the use of thiazide diuretics. We present a case report of a severe hypercalcemia due to a rare association and review the relev
Arch. Endocrinol. Metab.. Publicado em: 2015-02
-
3. Evaluation of the in vitro and in vivo anticancer properties of Moroccan propolis extracts
This investigation aimed to evaluate the in vitro and in vivo antitumor potential of a Moroccan propolis extracts. For in vitro assays, three mammalian tumor cell lines were used: BSR (hamster renal adenocarcinoma), Hep-2 (human laryngeal carcinoma) and P815 (murin mastocytoma). The propolis ethanolic extract as well as the ethyl acetate extract, exert an in
Revista Brasileira de Farmacognosia. Publicado em: 08/03/2012
-
4. Avaliação dos efeitos antineoplásicos do Amblyomin-X em carcinoma de células renais. / Evaluation of Amblyomin-X antineoplasic effects on renal cell carcinoma.
Introdução: O carcinoma de células renais metastático (CCRm) é um tumor altamente agressivo e resistente. Seu tratamento é baseado em terapia alvo molecular e citocinas. Avaliamos os efeitos antineoplásicos do Amblyomin-X, sobre CCR. Métodos: Avaliadas culturas de CCR RENCA e fibroblastos normais NIH/3T3 tratadas ou não com Amblyomin-X. Realizados e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/09/2011
-
5. Atividade anti-angiogênica e modulação das proteínas envolvidas na neoformação vascular por compostos bioativos da própolis / Anti-angiogenic activity and modulation of protein-involved in new vases formation by propolis bioactive compounds
Propolis is rich in bioactive compounds and widely used in alternative medicine as a preventive agent and/or in therapy. We evaluate the impact of polyphenol-rich fractions of propolis from different origins and types in the angiogenesis process in atherosclerotic lesions. The following samples of propolis were used: Red (red, Alagoas, Brazil), Green (green,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/07/2011
-
6. Citotoxicidade, cinética de proliferação, indução de apoptose e genotoxicidade do nicorandil e da N-(beta-hidroxietil) nicotinamida em cultura de células renais (786-O)
O nicorandil, um doador de óxido nítrico (NO) e ativador de canal de potássio ATP sensível (KATP), utilizado no tratamento da angina, tem como molécula precursora a N-(beta-hidroxietil) nicotinamida, não liberadora de NO. O nicorandil influencia a proliferação celular excessiva na disfunção renal, e a apoptose no tecido cardíaco pós isquemia. Mol
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/02/2011
-
7. Avaliação do vetor retroviral bicistrônico Codificador de endostatina e interleucina-2 Para utilização em terapia gênica anti-tumoral. / Evaluation of retroviral vector encoding bicistônico of endostatin and interleukin-2 for use in anti-tumor gene therapy
Gene therapy has been used in preclinical studies and clinical trials in order to assuage or cure a disease. Retroviral vectors are tools for gene transfer are widely used. Bicistronic vectors are attractive alternatives for treatment of complex disease. Endostatin (ES), the C-terminal fragment of collagen XVIII, is a potent angiogenesis inhibitor. At presen
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/07/2010
-
8. Prognostic kidney cancer nomogram. Study of Brazilian patients / Nomograma para definição prognóstica em câncer renal. Estudo com pacientes brasileiros
Introdução: as neoplasias renais sempre foram desafiadoras devido à história natural pouco previsível e pelo incessante acréscimo de conhecimentos que rapidamente se desenvolvem com o passar das últimas décadas. Como resultado, o anseio pela busca do conhecimento relacionado ao carcinoma de células renais (CCR) gerou grande opulência de novos trata
Publicado em: 2010
-
9. Estudo comparativo do efeito da Echinácea purpúrea e sorafenibe em células de adenocarcinoma renal humano em cultura / Comparative study of the effect of Echinacea purpurea and sorafenib in human renal adenocarcinoma cells in culture
Introduction: The renal cell carcinoma (CR) is relatively rare compared to other cancers. One of the most potent tumor mitogen, vascular endothelial growth factor, VEGF is regulated by numerous pathways, especially Ras and Akt, which are targets of many therapeutic agents, among them sorafenib. These signaling pathways play an important role in the developme
Publicado em: 2010
-
10. Estudo da atividade farmacolÃgica dos glicosÃdeos isolados da Herissantia crispa L. (Brizicky) e Sidastrum paniculatum (Fryxell) Malvaceae
The search for new therapies to cure the cancer, treatment of the inflammatory process and pain, are still objects of intensive investigations. It is believed that the natural products in general are important sources of biologically active chemicals with therapeutic potential and applicability, which are a source of diversity in structure, physicochemical p
Publicado em: 2009
-
11. Expression of IGF-II, IGF-IR, SF-1 and DAX-1 genes in pediatric and adult adrenocortical tumors / Expressão dos genes IGF-II, IGF-IR, SF-1 e DAX-1 em tumores adrenocorticais de crianças e adultos
Introduction: The molecular pathogenesis of adrenocortical tumors is heterogeneous and incompletely understood. Insulin-like growth factor II (IGF-II) overexpression has been demonstrated in adult adrenocortical carcinomas. IGF-II exerts its mitogenic effects through interaction with IGF-I receptor (IGF-IR). In addition, steroidogenic factor 1 gene (SF-1) an
Publicado em: 2008
-
12. Lack of association between matrix metalloproteinase-1 (MMP-1) promoter polymorphism and risk of renal cell carcinoma
OBJECTIVE: Investigate the possible association of insertion/deletion (2G/G) polymorphism at nucleotide -1607 of the MMP-1 promoter with the development and progression of renal cancer MATERIALS AND METHODS: In this study, we genotyped 217 individuals, 99 patients with renal cell carcinoma (RCC) and 118 controls without cancer. DNA specimens were extracted f
International braz j urol. Publicado em: 2007-10