Carbapenemases
Mostrando 1-12 de 44 artigos, teses e dissertações.
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1. Activity of ceftolozane-tazobactam and comparators against gram-negative bacilli: Results from the study for monitoring antimicrobial resistance trends (SMART – Brazil; 2016–2017)
Abstract Multi-drug resistant Gram-negative bacilli (GNB) have been reported as cause of serious hospital-acquired infections worldwide. The aim of this study was to investigate the in vitro activity of ceftolozane-tazobactam compared to other agents against GNB isolated from patients admitted to Brazilian medical centers between the years 2016 and 2017. Pre
Braz J Infect Dis. Publicado em: 2020-08
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2. Mobile genetic elements associated with carbapenemase genes in South American Enterobacterales
ABSTRACT Introduction: Carbapenem resistance in members of order Enterobacterales is a growing public health problem causing high mortality in developing and industrialized countries. Its emergence and rapid propagation worldwide was due to both intercontinental spread of pandemic strains and horizontal dissemination via mobile genetic elements (MGE) such a
Braz J Infect Dis. Publicado em: 2020-06
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3. Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil
Abstract INTRODUCTION: Acinetobacter baumannii are opportunistic bacteria, highly capable of acquiring antimicrobial resistance through the production of carbapenemases and aminoglycoside modifying enzymes (AMEs). METHODS: Carbapenemase and AME genes were investigated in A. baumannii recovered from inpatients of a Brazilian hospital. RESULTS: The key gen
Rev. Soc. Bras. Med. Trop.. Publicado em: 20/12/2019
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4. Emerging carbapenem-resistant Aeromonas spp. infections in Cali, Colombia
ABSTRACT Introduction: Aeromonas species are renowned enteric pathogens with virulence determinants linked to human diseases, such as gastroenteritis, skin, soft-tissue and muscle infections, and septicemia. A recent concern of resistance in this organism has emerged, especially the presence carbapenemases. Herein we describe a case series of emerging carba
Braz J Infect Dis. Publicado em: 25/11/2019
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5. High rate of detection of OXA-23-producing Acinetobacter from two general hospitals in Brazil
Abstract INTRODUCTION In recent decades, the prevalence of carbapenem-resistant Acinetobacter isolates has increased, and the production of oxacillinase (OXA)-type carbapenemases is the main mechanism underlying resistance. We evaluated OXA production from 114 Acinetobacter isolates collected between March and December 2013 from different clinical specimen
Rev. Soc. Bras. Med. Trop.. Publicado em: 05/09/2019
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6. Pseudomonas Aeruginosa: Virulence Factors and Antibiotic Resistance Genes
Abstract In this review, we explore some aspects of Pseudomonas aeruginosa virulence factors that are related to disease development in healthy organisms and resistance to antibiotics. This pathogen is one of the most clinically and epidemiologically important bacteria in Brazil, being the major cause of opportunistic infections. Among the virulence factors,
Braz. arch. biol. technol.. Publicado em: 09/06/2019
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7. Prevalência de carbapenemases em enterobactérias com sensibilidade diminuída aos carbapenêmicos isoladas em um hospital de referência terciária
RESUMO As infecções causadas por enterobactérias com resistência aos carbapenêmicos são um grave problema de saúde pública. Este trabalho tem como objetivo analisar os mecanismos de resistência relacionados com as enterobactérias com sensibilidade diminuída aos carbapenêmicos isoladas no Hospital Júlia Kubitschek (HJK) da Fundação Hospitalar d
J. Bras. Patol. Med. Lab.. Publicado em: 2018-04
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8. Isolation of blaNDM-producing Enterobacteriaceae in a public hospital in Salvador, Bahia, Brazil
ABSTRACT Carbapenemases have great importance in the global epidemiological scenario since infections with carbapenemase-producing bacteria are associated with high mortality, especially in hospitalized patients in intensive care units. This study describes two microorganisms producers of the New Delhi Metallo-b-lactamase, Klebsiella pneumoniae and Citrobact
Braz J Infect Dis. Publicado em: 2018-01
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9. β-lactamase-producing Gram-negative bacteria in an intensive care unit in southern Brazil
ABSTRACT The present study evaluated the antimicrobial susceptibility profile, β-lactamase production, and genetic diversity of Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter spp. using phenotypic identification, antimicrobial susceptibility testing, and β-lactamase phenotypic detection. Isolates were obtained from patients in an intensive c
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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10. Phenotypic methods for screening carbapenem-resistant Enterobacteriaceae and assessment of their antimicrobial susceptibility profile
Abstract INTRODUCTION: In this study, we used phenotypic methods to screen carbapenem-resistant Enterobacteriaceae (CREs) and evaluated their antimicrobial sensitivity profile. METHODS: One hundred and seventy-eight CREs were isolated at a university hospital in south Brazil in a one-year period. Samples were assessed using disk diffusion tests with inhib
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-03
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11. Detecção de genes de resistência a antimicrobianos em Klebsiella pneumoniae produtoras de betalactamases e carbapenemases por culturas de vigilância de pacientes em uma unidade de terapia intensiva no Rio de Janeiro, Brasil
RESUMO Introdução: O aumento da incidência de microrganismos multirresistentes é considerado um dos principais problemas de saúde pública. Uma das rotinas incluídas na prática hospitalar é a busca de pacientes colonizados e/ou infectados. Objetivo: Avaliar a variabilidade genética e as relações clonais de K. pneumoniae produtoras de betalactama
J. Bras. Patol. Med. Lab.. Publicado em: 2016-10
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12. Mechanisms of carbapenem resistance in endemic Pseudomonas aeruginosa isolates after an SPM-1 metallo-β-lactamase producing strain subsided in an intensive care unit of a teaching hospital in Brazil
Carbapenem-resistance mechanisms are a challenge in the treatment of Pseudomonas aeruginosa infections. We investigated changes in P. aeruginosa carbapenem-resistance determinants over a time period of eight years after the emergence of São Paulo metallo-β-lactamase in a university hospital in Rio de Janeiro, Brazil. Patients admitted to the intensive care
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-09