Carbamazepine
Mostrando 13-24 de 127 artigos, teses e dissertações.
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13. A influência da piperina na biodisponibilidade de fármacos: uma abordagem molecular
Piperine is the major alkaloid of Piper nigrum Linn., used as a spice and in folk medicine. We present a molecular docking study supporting experimental data on the enhancement in bioavailability of propranolol, theophylline, phenytoin, nevirapine, nimesulide, pyrazinamide, carbamazepine, and spartein in the presence of piperine. The complex formed with pipe
Quím. Nova. Publicado em: 2014
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14. Determinação simultânea de topiramato, carbamazepina, fenitoína e fenobarbital em plasma empregando cromatografia a gás com detector de nitrogênio e fósforo
Topiramate and the other frequently co-administered antiepileptic drugs carbamazepine, phenytoin and phenobarbital were determined in 100 µL plasma samples by gas chromatography with nitrogen phosphorus detection (GC-NPD), after a one-step liquid-liquid extraction with ethyl acetate, followed by flash methylation with trimethylphenylammonium hydroxide. Tota
Quím. Nova. Publicado em: 2013
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15. Biomimetic oxidation of carbamazepine with hydrogen peroxide catalyzed by a manganese porphyrin
This laboratory project is planned for an undergraduate chemistry laboratory in which students prepare a manganese porphyrin able to mimic the oxidative metabolism of carbamazepine, one of the most frequently prescribed drugs in the treatment of epilepsy. The in vitro oxidation of carbamazepine results in the formation of the corresponding 10,11-epoxide, the
Química Nova. Publicado em: 2012
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16. High performance thin layer chromatographic determination of nifedipine in human serum after liquid-liquid extraction
A method using HPTLC for quantitation of nifedipine in serum was developed and validated. It includes a liquid-liquid extraction, and carbamazepine as internal standard. Chloroform: ethyl acetate: cyclohexane (19:2:2, v/v/v) was the mobile phase. The method showed good relationship (r = 0.996) (2.00 to 25.00 ng/band, corresponding to 0.02 and 0.25 ng/µL in
Química Nova. Publicado em: 2012
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17. Validação psicométrica da versão português-Brasil do Liverpool Adverse Events Profile (LAEP) em pacientes com epilepsia parcial sintomática e epilepsia generalizada idiopática. / Psychometric Validation of the Portuguese-Brazilian Version of the Liverpool Adverse Events Profile in Patients with Symptomatic Partial and Idiopathic Generalized Epilepsies
Purpose: To report the translation, cultural adaptation and validation of the Liverpool Adverse Events Profile (LAEP) into a PortugueseBrazilian version and evaluate its reliability and validity in patients with symptomatic partial (SPE) and idiopathic generalized epilepsies (IGE) (ILAE, 1989). LAEP is a scale to measure patients perception about adverse eff
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/06/2011
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18. An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay
The Caco-2 cell line has been used as a model to predict the in vitro permeability of the human intestinal barrier. The predictive potential of the assay relies on an appropriate in-house validation of the method. The objective of the present study was to develop a single HPLC-UV method for the identification and quantitation of marker drugs and to determine
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-06
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19. Análise de fatores relacionados à resistência ao tratamento com drogas anti-epilepticas em epilepsia de lobo temporal mesial / Analysis of factors related to anti-epileptic drug resistance in mesial temporal lobe epilepsy
The objective of the present work was to investigate the relationship between brain MRI and clinical characteristics and patterns of antiepileptic drug (AED) response in patients with mesial temporal lobe epilepsy (MTLE).In order to do that,one hundred sixty five MTLE patients were divided into seizure-free with AED (50 AEDresponders, 31 women), 87 pharmacor
Publicado em: 2011
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20. Qualificação do desempenho e validação do processo de obtenção de comprimidos por compressão direta em escala piloto / Performance qualification and process validation of direct compression tablet development at pilot scale
Estudos de qualificação e validação de processos são amplamente requisitados por agências regulatórias na produção de medicamentos. Entretando, uma abordagem pouco explorada pela literatura é o emprego de equipamentos qualificados e processos validados em estudos de formulação. O presente trabalho objetiva desenvolver uma proposta de qualificaç�
Publicado em: 2011
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21. Determination of carbamazepine in pharmaceutical formulations
O objetivo desse trabalho foi avaliar a qualidade de cinco formulações de carbamazepina na dosagem de 200,00 mg: medicamento referência Tegretol® (Novartis), medicamento genérico (indústria nacional), medicamento similar (indústria nacional) e cápsulas do mesmo medicamento obtidas de duas farmácias de manipulação da cidade do Natal, RN. Os ensaios
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2010-09
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22. Efeito da carbamazepina na reabsorção de água pelo ducto coletor medular interno de ratos normais e de ratos com diabetes insípido nefrogênico induzido pelo lítio / Effect of carbamazepine on water absorption in the inner medullary collecting duct from normal rats and from rats with lithium-induced diabetes insipidus
Carbamazepine (Carba) is an anticonvulsant and a psychotropic medication commonly used in the treatment of patients with intellectual disability (ID). This drug has been used to try to decrease the urinary volume in Diabetes Insipidus (DI) because Carba presents an antidiuretic effect, but the incidence of the hyponatremia in neurological patients is a commo
Publicado em: 2010
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23. Desenvolvimento de dispersões sólidas microparticuladas contendo carbamazepina por spray congealing / Development of carbamazepine microparticulated solid dispersions by spray congealing.
O melhoramento das propriedades de dissolução de produtos farmacêuticos é extremamente importante, visto que houve um aumento de fármacos de baixa solubilidade disponibilizados no mercado farmacêutico nos últimos tempos. Várias técnicas têm sido utilizadas para melhorar as propriedades de dissolução destes fármacos como a cominuição, o uso de
Publicado em: 2010
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24. AvaliaÃÃo da equivalÃncia farmacÃutica da Carbamazepina e Diazepam comercializados no Programa de FarmÃcia popular do Brasil / Assessment pharmaceutical equivalence of carbamazepine and diazepam marketed in the brazil popular pharmacy program
Two drugs are considered pharmaceutically equivalent when both contain the same drug (base, salt or ester of the same active ingredient), at the same dosage and pharmaceutical form determined in vitro. In Brazil, the allopathic drugs are classified into three cathegories when registered in the Brazilian health surveillance agency (AgÃncia Nacional de Vigil�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/01/2009