Bony Callus
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Efeitos do ibandronato de sÃdio na consolidaÃÃo de fraturas femorais de ratos tratados com haste intramedular / Effects of ibandronate on femoral fractures healing in rats treated with intramedullary sistem
O Ibandronato de sÃdio à um medicamento utilizado para o tratamento clÃnico da osteoporose e por ter aÃÃo anticatabÃlica e causar apoptose no osteoclasto, uma importante cÃlula responsÃvel pela remodelaÃÃo Ãssea, foi hipotetizado um efeito na consolidaÃÃo fraturas na fase de remodelaÃÃo do calo Ãsseo. O objetivo deste estudo foi avaliar o efe
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/03/2011
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2. Influence of methotrexate on bone healing of a defect simulating a fracture in rat mandible / Avaliação do efeito do metotrexato na reparação tecidual em um defeito ósseo simulando fratura de mandíbula em ratos
Purpose: The present study aims to verify the effect of high and low dose of methotrexate (MTX) treatment on bone repair of mandibular fractures in rats. Methods: The experimental model employed consists in creating a defect in rat mandible, similar to a fracture. Eighty rats were distributed in 4 groups of 20 animals that received, intraperitoneally: saline
Publicado em: 2008
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3. Rescue of Impaired Fracture Healing in COX-2−/− Mice via Activation of Prostaglandin E2 Receptor Subtype 4
Although the essential role of cyclooxygenase (COX)-2 in fracture healing is known, the targeted genes and molecular pathways remain unclear. Using prostaglandin E2 receptor (EP)2 and EP4 agonists, we examined the effects of EP receptor activation in compensation for the lack of COX-2 during fracture healing. In a fracture-healing model, COX-2−/− mice sh
American Society for Investigative Pathology.
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4. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular endothelial growth factor, VEGF, is of particular interest because of its ability to induce neovascularization (angiogenesis). To determine whether VEGF is required for bone repair, we inhibited VEGF activity during secondary bone healing
The National Academy of Sciences.