Biological Response
Mostrando 1-12 de 1589 artigos, teses e dissertações.
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1. BIOMARCADORES MOLECULARES DE DOENÇAS HUMANAS: CONCEITOS FUNDAMENTAIS, MODELOS DE ESTUDO E APLICAÇÕES CLÍNICAS
Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose presence or alteration in metabolic pathways indicate the response of a biological system to a disturbance caused by internal or external factors. The search for biomarkers has allowed deepening the knowledge of complex pathophysiological mechanisms of diseases, interactions w
Química Nova. Publicado em: 2022
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2. Mycosis fungoides and Sézary syndrome: focus on the current treatment scenario
Abstract Cutaneous T-cell lymphomas are a heterogeneous group of lymphoproliferative disorders, characterized by infiltration of the skin by mature malignant T cells. Mycosis fungoides is the most common form of cutaneous T-cell lymphoma, accounting for more than 60% of cases. Mycosis fungoides in the early-stage is generally an indolent disease, progressing
An. Bras. Dermatol.. Publicado em: 2021-08
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3. [5]Helicene-Scaffold Fluorescence Sensing for Selective Detection of Au3+ Ions and Gold Nanoparticle
A new quenching fluorescence sensor (MDP) with high productivity was easily synthesized from a [5]helicene anhydride derivative and propargyl bromide. This MDP sensor has significant photophysical properties, including high fluorescence emission and a large Stokes shift, and it exhibits selectivity and an excellent detection response in distinguishing Au3+ i
J. Braz. Chem. Soc.. Publicado em: 2021-04
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4. Follow-up and outcome of the twelve-year experience in adult patients with acute promyelocytic leukemia
ABSTRACT Acute promyelocytic leukemia is a subtype of acute myeloid leukemia, characterized by the presence of neoplastic promyelocytes, due to the reciprocal balanced translocation between chromosomes 15 and 17. Currently, with the use of agents that act directly on this molecular change, such as all-trans retinoic acid and arsenic trioxide, APL has shifted
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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5. BDNF Val66Met polymorphism and resilience in major depressive disorder: the impact of cognitive psychotherapy
Objective: Clinical and biological correlates of resilience in major depressive disorder are scarce. We aimed to investigate the effect of the Val66Met polymorphism in the BDNF gene on resilience scores in major depressive disorder patients and evaluate the polymorphism’s moderation effect on resilience scores in response to cognitive therapy. Method: A
Braz. J. Psychiatry. Publicado em: 2021-02
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6. EFECTO DE LA ADICIÓN DE POLÍMEROS DE CADENA CORTA SOBRE LA ESTRUCTURA QUÍMICA, PROPIEDADES MECÁNICAS, TÉRMICAS Y BIOLÓGICAS DE POLIURETANOS SINTETIZADOS CON DIISOCIANATOS ALIFÁTICOS Y ACEITE DE HIGUERILLA
The objective of this research was to synthesize biocompatible polyurethanes, with suitable mechanical properties to be used as biomaterials. Polyurethanes were synthesized with polyols derived from castor oil and isophorone diisocyanate (IPDI), hexamethylene diisocyanate and 4,4’-methylenebis (cyclohexyl isocyanate), with the addition of polycaprolactone/
Quím. Nova. Publicado em: 2021-01
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7. Response of grey slug to entomopathogenic nematodes
ABSTRACT Biological control using entomopathogenic nematodes (EPNs) is known as an ecofriendly strategy in integrated pest management. The terrestrial slug Parmacella ibera is a major pest of vegetables and citrus trees in north of Iran. The heavy costs and environmental concerns of synthetic molluscicides led the study to use EPNs, against the slug P. ibera
Bragantia. Publicado em: 2020-12
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8. Synergistic Supramolecular Effect on the Electro-Oxidation of Biological Relevant Molecules: A Novel Sensor for Simultaneous Determination of Epinephrine and Uric Acid in Human Urine Using MWCNT and a Copper(II) Complex
In this paper a novel supramolecular strategy to improve the efficiency of a voltammetric sensor to determine two biologically relevant molecules (epinephrine (EP) and uric acid (UA)) is presented. The strategy is based on the use of a glassy carbon electrode modified with a copper(II) complex ([Cu(H2dimpy)Cl]PF6) adsorbed on multi-walled carbon nanotubes (M
J. Braz. Chem. Soc.. Publicado em: 2020-11
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9. Tópicos Emergentes em Insuficiência Cardíaca: Terapias Intervencionistas na Insuficiência Cardíaca
In this paper a novel supramolecular strategy to improve the efficiency of a voltammetric sensor to determine two biologically relevant molecules (epinephrine (EP) and uric acid (UA)) is presented. The strategy is based on the use of a glassy carbon electrode modified with a copper(II) complex ([Cu(H2dimpy)Cl]PF6) adsorbed on multi-walled carbon nanotubes (M
Arq. Bras. Cardiol.. Publicado em: 2020-11
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10. Sydney Melancholia Prototype Index (SMPI): translation and cross-cultural adaptation to Brazilian Portuguese
Abstract Introduction Depression is possibly not a single syndrome but rather comprises several subtypes. DSM-5 proposes a melancholia specifier with phenotypic characteristics that could be associated with clinical progression, biological markers or therapeutic response. The Sydney Melancholia Prototype Index (SMPI) is a prototypic scale aimed to improve
Trends Psychiatry Psychother.. Publicado em: 2020-09
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11. Panic disorder respiratory subtype: psychopathology and challenge tests – an update
Panic disorder (PD) pathophysiology is very heterogeneous, and the discrimination of distinct subtypes could be very useful. A subtype based on respiratory symptoms is known to constitute a specific subgroup. However, evidence to support the respiratory subtype (RS) as a distinct subgroup of PD with a well-defined phenotype remains controversial. Studies hav
Braz. J. Psychiatry. Publicado em: 2020-08
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12. Precision non-implantable neuromodulation therapies: a perspective for the depressed brain
Current first-line treatments for major depressive disorder (MDD) include pharmacotherapy and cognitive-behavioral therapy. However, one-third of depressed patients do not achieve remission after multiple medication trials, and psychotherapy can be costly and time-consuming. Although non-implantable neuromodulation (NIN) techniques such as transcranial magne
Braz. J. Psychiatry. Publicado em: 2020-08