Biodosimetry
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. A dose-response curve for biodosimetry from a 6 MV electron linear accelerator
Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical paramet
Braz J Med Biol Res. Publicado em: 26/05/2015
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2. Adequacy of cytogenetic dosimetry to evaluate partial and total body irradiation / AdequaÃÃo da dosimetria citogenÃtica para avaliaÃÃo de irradiaÃÃo parcial e de corpo inteiro
The majority of human exposures to ionizing radiation involves partial human body irradiation. Thus, the use of cytogenetic dosimetry, when this aspect is not taken into account, can result in dose underestimation to the irradiated subject. In this context, this research studied methodological parameters of biodosimetry, such as cell culture time, time of Co
Publicado em: 2009
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3. Curva de calibração para dosimetria biológica de campo misto nêutron-gama pelo método citogenético convencional
A contagem de alterações cromossômicas em linfócitos do sangue periférico tem sido utilizada para determinar a dose de radiação gama absorvida em indivíduos expostos acidental ou ocupacionalmente. No entanto, não há muitos estudos acerca dos efeitos dos campos mistos nêutron-gama. A radiobiologia de nêutrons tem grande importância porque em usin
Publicado em: 2009
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4. Biodosimetry for dose assessment of partial-body exposure: a methodological improvement
Este trabalho avaliou a estimativa da dose de radiação simulando uma exposição parcial do corpo através da irradiação in vitro de amostras de sangue misturadas com amostras não irradiadas. Foi observado que o prolongamento do tempo de cultura permite que a real fração de linfócitos em M1 contendo aberrações cromossômicas seja detectada, propici
Brazilian Archives of Biology and Technology. Publicado em: 2008-12
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5. AplicaÃÃo da citogenÃtica na avaliaÃÃo da radioproteÃÃo de traumatologistas do Recife / Application of cytogenetics for evaluating radioprotection conditions of traumatologists in Recife
Among the activities involving the application of ionizing radiation in medicine, fluoroscopic procedures correspond to the major source of irradiation to doctors. Fluoroscopy consists of X-ray equipment coupled with an image intensifier. This methodology permits a real time visualization of interior of the patientâs body during a surgery. A recent study pe
Publicado em: 2006
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6. Emprego das aberraÃÃes cromossÃmicas instÃveis e micronÃcleos no biomonitoramento individual: estudo comparativo
Biodosimetry is based on the investigation of radioinduced biological effects in order to correlate them with the absorbed dose. The quantification of unstable chromosome aberrations and micronuclei, in peripheral blood lymphocytes, are two methods commonly used in biodosimetry. In this context, the aim of this research was to compare these methods in the bi
Publicado em: 2005
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7. Comparison of UV Inactivation of Spores of Three Encephalitozoon Species with That of Spores of Two DNA Repair-Deficient Bacillus subtilis Biodosimetry Strains
When exposed to 254-nm UV, spores of Encephalitozoon intestinalis, Encephalitozoon cuniculi, and Encephalitozoon hellem exhibited 3.2-log reductions in viability at UV fluences of 60, 140, and 190 J/m2, respectively, and demonstrated UV inactivation kinetics similar to those observed for endospores of DNA repair-defective mutant Bacillus subtilis strains use
American Society for Microbiology.
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8. UV Resistance of Bacillus anthracis Spores Revisited: Validation of Bacillus subtilis Spores as UV Surrogates for Spores of B. anthracis Sterne
Recent bioterrorism concerns have prompted renewed efforts towards understanding the biology of bacterial spore resistance to radiation with a special emphasis on the spores of Bacillus anthracis. A review of the literature revealed that B. anthracis Sterne spores may be three to four times more resistant to 254-nm-wavelength UV than are spores of commonly u
American Society for Microbiology.
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9. Release of Inorganic Phosphate from Irradiated Yeast: Radiation Biodosimetry and Evaluation of Radioprotective Compounds
When cells of bakers' yeast, Saccharomyces cerevisiae, were irradiated with ionizing radiation, inorganic phosphate, ninhydrin-reactive material, and substances absorbing at 260 mμ were released into the suspending medium. The amount of inorganic phosphate released depended on the radiation dose and on the temperature and pH during irradiation. The concentr