Bioanalysis
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Flow Analysis: Looking Back and Forward
Flow analysis changed significantly the way of performing chemical analysis by (i) mechanization of analytical procedures in a continuous flowing stream with minimal sample intercontamination; (ii) analytical measurements without attaining chemical equilibria, thus increasing the applicability of kinetic methods and allowing the exploitation of non-quantitat
J. Braz. Chem. Soc.. Publicado em: 2018-05
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2. Nimodipine determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS-MS). / Determinação de nimodipino em plasma humano através de cromatografia líquida de alta eficiência acoplada à espectrometria de massa (LC-MS-MS)
Um método rápido, sensível e específico de Cromatografia Líquida de Alta Eficiência acoplada à Espectrometria de Massa (LC-MS-MS) foi desenvolvido para determinar nimodipino (analito) em plasma humano usando dibucaína como padrão interno (PI). O analito (m/z 418,6 >342,6) e o PI (m/z 344,2 >271,0) foram extraídos de amostras de plasma através de e
Publicado em: 2005
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3. International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma
An international interlaboratory quality control program for measurement of antiretroviral drugs was initiated. The first round was confined to protease inhibitors and showed large variability in the performance of participating laboratories. The results demonstrate the need for and utility of an ongoing quality control program in this area of bioanalysis.
American Society for Microbiology.
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4. A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles
The rapid and sensitive determination of pathogenic bacteria is extremely important in biotechnology, medical diagnosis, and the current fight against bioterrorism. Current methods either lack ultrasensitivity or take a long time for analysis. Here, we report a bioconjugated nanoparticle-based bioassay for in situ pathogen quantification down to single bacte
National Academy of Sciences.
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5. “Fit-for-Purpose” Method Validation and Application of a Biomarker (C-terminal Telopeptides of Type 1 Collagen) in Denosumab Clinical Studies
Biomarkers are used to study drug effects, exposure–response relationships, and facilitate early decision making during development. Denosumab, a fully human monoclonal antibody against receptor activator of nuclear factor-κB ligand, profoundly inhibits bone resorption. C-terminal telopeptides of type I collagen (CTx), a bone resorption biomarker, provide
Springer US.