Beta Lactam Antibiotics
Mostrando 13-24 de 567 artigos, teses e dissertações.
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13. Identification, antimicrobial resistance and genotypic characterization of enterococcus spp. isolated in Porto Alegre, Brazil
In the past two decades the members of the genus Enterococcus have emerged as important nosocomial pathogens worldwide. In the present study, we evaluated the antimicrobial resistance and genotypic characteristics of 203 Enterococcus spp. recovered from different clinical sources from two hospitals in Porto Alegre, Rio Grande do Sul, Brazil. The species were
Publicado em: 2010
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14. Caracterização fenotípica e molecular de isolados clínicos de Pseudomonas aeruginosa produtores de metalo-beta-lactamases
A produção de metalo-beta-lactamases (MβL) é um importante mecanismo de resistência aos carbapenêmicos detectado com aumentada freqüência entre isolados clínicos de Pseudomonas aeruginosa recuperados no Brasil. Este estudo foi desenvolvido com o objetivo de avaliar o perfil de sensibilidade aos antimicrobianos, pesquisar a ocorrência de Mβ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/12/2009
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15. Analise de multirresiduos de antibioticos anfenicois e beta -lactamicos em leite por cromatografia liquida de alta eficiencia acoplada ao detector de massas / Analysis of multirresiduos of antibiotics anfenicois and beta -lactam antibiotics in milk by high performance liquid chromatography coupled to mass detector
A presença de resíduos de antibióticos no leite resulta da aplicação de diferentes substâncias antimicrobianas no gado leiteiro para o tratamento de infecções e uso profilático na prevenção de doenças e como aditivos adicionados à ração para promover o crescimento do animal. A utilização indiscriminada dos antibióticos pode estar associada
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/07/2009
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16. Estudo comparativo de fatores de virulência em isolados clínicos de Pseudomonas aeruginosa produtores e não produtores de metalo- ß-lactamase SPM-1
The invasion abilities, colonization and tissue damage presented by P. aeruginosa are due to the multiples virulence factors produced by the microorganism during the pathogenesis. Clinical isolates of SPM-1 metallo-β-lactamase Pseudomonas aeruginosa (SPM-1 MβL) from nosocomial infections present high rates morbidity and mortality and represent epid
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/05/2009
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17. Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado
The extended-spectrum beta-lactamases (ESBL) represent an important mechanism of resistance to beta-lactam antibiotics. Such enzymes have spread among members of the Enterobacteriaceae family, which are responsible for infections related to health care, particularly nosocomial infections. Objectives: (a) To determine the prevalence of ESBL producing Escheric
Publicado em: 2009
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18. Influence of sodium diclofenac on absorption, serum concentration and excretion of amoxicillin in rats / Influencia do diclofenaco sodico na absorção, concentração serica e excreção da amoxicilina : estudos em ratos
O uso de antimicrobianos e de antiinflamatórios é prática comum na odontologia, embora haja escassez de trabalhos sobre seu uso simultâneo. Portanto, o objetivo deste trabalho foi avaliar, em ratos, os efeitos do diclofenaco sódico na absorção, concentração sérica e excreção da amoxicilina utilizando a técnica de perfusão tecidual e o método m
Publicado em: 2006
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19. A study on clavulanic acid production by Streptomyces clavuligerus in batch, fed-batch and continuous processes
Clavulanic acid (CA) is a potent inhibitor of beta-lactamases, enzymes that are responsible for the hydrolysis of beta-lactam antibiotics. It is a secondary metabolite produced by the filamentous aerobic bacterium Streptomyces clavuligerus in submerged cultivations. In the present work clavulanic acid production in batch, fed-batch and continuous bioreactors
Brazilian Journal of Chemical Engineering. Publicado em: 2005-12
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20. A fuzzy logic algorithm for identification of the harvesting threshold during PGA production by Bacillus megaterium
Penicillin G acylase (PGA) is an important enzyme used as biocatalyst in the production of semisynthetic beta-lactam antibiotics. Many microorganisms produce this enzyme and recombinant Escherichia coli has been preferred use for industrial applications. Bacillus megaterium is one of the microorganisms that excretes this enzyme into the medium. As a conseque
Brazilian Journal of Chemical Engineering. Publicado em: 2005-12
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21. Concentrações plasmaticas e salivares e efeito sobre a microbiota oral de duas formulações de amoxicilina : estudo em voluntarios sadios
The plasmatic and salivary concentration of amoxicillin(AMO)875mg and its effects on oral microbiota in healthy volunteers were assessed in an open, randomized, two-period crossover designo A single 875 mg oral dose of AMO (Amoxicillin-EMS- test formulation and Amoxil@- reference formulation) was administered to ali volunteers observing 1-week intervaI betwe
Publicado em: 2005
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22. Intensificated process of hydrolysis of penicillin G and purification of the products in a multi-stage couter-current reactor / Processo intensificado de hidrolise enzimatica de penicilina G e purificação dos produtos em reator multi-estagio e contra-corrente
This work studies the enzymatic hydrolysis of penicillin G (PenG) into 6-aminopenicillanic acid (6-APA) and phenylacetic acid (PAA). In a multi-stage countercurrent reactor and at low pH, the enzymatic reaction takes place in the aqueous phase and the products are separated between the aqueous phase and organic phase (butyl acetate - BuAc). Furthermore, 6-AP
Publicado em: 2004
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23. Application of Fuzzy Logic in the Production of Penicillin G Acylase in Bacillus megaterium Cultivations. / Aplicação da lógica fuzzi na produção de penicilina G Acilase em cultivos de Bacillus megaterium.
Penicillin G acylase (PGA) is an important enzyme for the pharmaceutical industry. This enzyme has industrial use in the hydrolysis of penicillin G to obtain 6-aminocephalosporanic acid (6-APA), essential intermediate for the production of beta-lactam antibiotics. Many microorganisms produce PGA, but Bacillus megaterium is one of the few that excretes the en
Publicado em: 2003
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24. In vitro activity of fluoroquinolones (gatifloxacin, levofloxacin and trovafloxacin) and seven other antibiotics against Streptococcus pneumoniae
In recent years, the level of resistance of S. pneumoniae to beta-lactam and/or macrolides has increased around the world including some countries in South America. Because of this resistance, it is necessary to test the therapeutic alternatives for treating this pathogen, including the newer quinolones. This study was carried out in order to compare the in
Brazilian Journal of Infectious Diseases. Publicado em: 2001-04