Beer Law
Mostrando 1-12 de 48 artigos, teses e dissertações.
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1. UPLC-MS/MS and Dushman reaction based spectrophotometric method for determination of Ceftazidime, an antibiotic, in medicinal formulation
ABSTRACT: Two analytical methods were developed, one utilizing sensitive UPLC-MS/MS method while other being the spectrophotometric method exploiting the Dushman reaction. Both methods were validated based on ICH guidelines and were successfully applied to quantitate the drug in marketed formulation. UPLC-MS/MS method responded linearly in the range of 1.6 �
Food Sci. Technol. Publicado em: 2021-03
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2. STUDY OF SPECTROPHOTOMETRIC CHARACTERISTICS OF THE CHARGE TRANSFER COMPLEX OF TAURINE DRUG WITH 7,7,8,8-TETRACYANOQUINODIMETHANE
A new spectrophotometric method was developed for the determination of taurine using 7,7,8,8-tetracyanoquinodimethane (TCNQ). The method was based on the formation of charge transfer (CT) complex of this drug as n-electron donor with the π-acceptor TCNQ. TCNQ was found to react with taurine to produce a kind of yellow complex. The spectrum obtained for taur
Quím. Nova. Publicado em: 2020-09
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3. NEW APPLICATIONS FOR AMOXICILLIN DETERMINATION IN PURE FORM AND PHARMACEUTICALS BASED ON IODATE-IODIDE MIXTURE: TITRIMETRY AND SPECTROSCOPY STUDIES
Three simple methods are described for the determination of amoxicillin (AMX) in bulk drug and dosage forms using iodate-iodide mixture reagent. These methods employed the well-known analytical reaction between iodate-iodide mixture in the presence of acid solution. The iodide oxidized by iodate to iodine in an amount equivalent to the -COOH group present in
Quím. Nova. Publicado em: 2020-01
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4. Development and Validation of a New Spectrophotometric Method for the Determination of Cephalexin Monohydrate in Pure Form and Pharmaceutical Formulations
A simple, fast, sensitive and accurate spectrophotometric method has been developed for the quantitative determination of cephalexin monohydrate in dosage form and in commercial formulations. The method involves the addition of CeIV to cephalexin in acidic medium, followed by the determination of residual CeIV by reacting with a fixed amount of methyl orange
J. Braz. Chem. Soc.. Publicado em: 2016-05
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5. SIMPLE AND SELECTIVE SPECTROPHOTOMETRIC ASSAY OF DIETHYLCARBAMAZINE CITRATE USING 2,3-DICHLORO-5,6-DICYANO-
p -BENZOQUINONE AND 2,4-DINITRO PHENOLTwo simple, rapid and inexpensive spectrophotometric methods are described for the determination of diethylcarbamazine citrate (DEC) in bulk drug and formulations. The methods are based on the charge–transfer (CT) complexation reaction involving DEC as the n- donor and 2,3-dichloro-5,6-dicyano-
p -benzoquinone [DDQ] (method A) and 2,4-dinQuím. Nova. Publicado em: 2015-06
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6. Determinação espectrofotométrica por injeção em fluxo de glifosato em formulações comerciais de herbicidas
A flow injection spectrophotometric procedure for the determination of glyphosate in commercial formulations of herbicides is proposed. The determination is based on the reaction of glyphosate and p-dimethylaminocinnamaldehyde, in acid medium, yielding a colored compound (l máx = 495 nm). Under optimal conditions, Beer's law is obeyed in a concentration ran
Química Nova. Publicado em: 2012
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7. Development of a simple UV-spectrophotometric method for the determination of lansoprazole and study of its degradation profile
A UV-spectrophotometric method is described for the determination of lansoprazole (LAN). The method is based on the measurement of the absorbance of LAN solution in acetonitrile at 281 nm. The system obeyed Beer's law over the concentration range of 1.25-25.0 µg/mL. The degradation behavior of LAN was investigated under dry heat treatment, UV-degradation, a
Química Nova. Publicado em: 2012
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8. Studies on the development of spectrophotometric method for the determination of haloperidol in pharmaceutical preparations
A spectrophotometric method based on the formation of ion-pair complex between haloperidol and eriochrome black T (EBT) at pH 1.85 has been described. The formed complex was extracted quantitatively into chloroform and measured at 510 nm. Infra red (IR) studies were performed to confirm the formation of ion-pair complex. Beer's law was obeyed in the concentr
Química Nova. Publicado em: 2012
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9. Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r
A highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lmax) at 565 nm. Beer's law is obeyed in t
Química Nova. Publicado em: 2011
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10. Sequential injection analysis system with spectrophotometric detection for determination of norfloxacin and ciprofloxacin in pharmaceutical formulations
This work proposes a sequential injection analysis (SIA) system for the spectrophotometric determination of norfloxacin (NOR) and ciprofloxacin (CIP) in pharmaceutical formulations. The methodology was based on the reaction of these drugs with p-(dimethylamino)cinnamaldehyde in micellar medium, producing orange colored products (λmax = 495 nm). Beer´s law
Química Nova. Publicado em: 2011
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11. Spectrophotometric determination of nevirapine using tetrathiocyanatocobalt(II) ion as a reagent
A simple and rapid spectrophotometric method for the determination of nevirapine is described. The method is based on the reaction of nevirapine with tetrathiocyanatocobalt(II) ion in buffer of pH 4 to form the corresponding complex. Beer's law is obeyed in the range of 0.2 - 2.0 µg mL-1 for nevirapine. The optical parameters such as molar absorptivity, San
Eclética Química. Publicado em: 2010-09
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12. Development and validation of spectrophotometric method for the determination of DPP-4 inhibitor, sitagliptin, in its pharmaceutical preparations
A simple, sensitive and reproducible spectrophotometric method was developed for the determination of sitagliptin phosphate in bulk and in pharmaceutical formulations. The proposed method is based on condensation of the primary amino group of sitagliptin phosphate with acetyl acetone and formaldehyde producing a yellow colored product, which is measured spec
Eclética Química. Publicado em: 2010-09