Bactericidal And Cytotoxic Effects
Mostrando 1-8 de 8 artigos, teses e dissertações.
-
1. Miscellaneous Diterpenes from the Aerial Parts of Plectranthus ornatus Codd
Five new diterpenes derivatives named as ornatin A, B, C, D and E, in addition to six known related diterpenes were isolated from the aerial parts of cultivated specimens of Plectranthus ornatus. The structures were elucidated using a combination of 1D/2D nuclear magnetic resonance (NMR) spectroscopy, high-resolution electrospray ionization mass spectrometry
J. Braz. Chem. Soc.. Publicado em: 2017-06
-
2. Structural and functional caracterization of L-aminoácido oxidases isolated from snake Bothrops venoms / Caracterização funcional e estrutural de L-aminoácido oxidases isoladas de venenos de serpentes do gênero Bothrops
The aim of this project was the isolation of three L-aminoacid oxidases from Bothrops jararaca, Bothrops moojeni and Bothrops pirajai snake venoms, respectively, in addition to their biochemical, enzymatic, pharmacological and toxicological characterization. They were named BjarLAAO-I, BmooLAAO-I and BpirLAAO-I, respectively, and their isolation involved two
Publicado em: 2008
-
3. Caracterização bioquímica e funcional de uma nova L-aminoácido oxidase isolada da peçonha da serpente Bothrops pirajai
In this work we describe the isolation of a new L-amino acid oxidase (LAAO) referred to as BpirLAAO-I from Bothrops pirajai snake venom, which was highly purified using a combination of molecular exclusion, affinity and hydrophobic chromatography steps. BpirLAAO-I is a homodimeric acidic glycoprotein (approximate Mr and pI of 130,000 and 4.9, respectively),
Publicado em: 2007
-
4. CaracterizaÃÃo bioquÃmica e funcional de uma nova L-aminoÃcido oxidase isolada da peÃonha da serpente Bothrops pirajai
In this work we describe the isolation of a new L-amino acid oxidase (LAAO) referred to as BpirLAAO-I from Bothrops pirajai snake venom, which was highly purified using a combination of molecular exclusion, affinity and hydrophobic chromatography steps. BpirLAAO-I is a homodimeric acidic glycoprotein (approximate Mr and pI of 130,000 and 4.9, respectively),
Publicado em: 2007
-
5. Bactericidal and cytotoxic effects of hypothiocyanite-hydrogen peroxide mixtures.
Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of thiocyanate can actually potentiate the bactericidal and cytotoxic effects of hydrogen
-
6. The Bactericidal And Cytotoxic Effects Of Antimicrobial Wound Cleansers
Objective: Wound care is a part of daily activity for many athletic trainers. Knowing which cleansers are effective against the bacteria that most commonly cause infection and whether they are toxic to healthy cells enables athletic trainers to make educated decisions on which cleanser to use. We compared the bactericidal effectiveness and cytotoxicity to hu
attr.
-
7. High Therapeutic Index of Factor C Sushi Peptides: Potent Antimicrobials against Pseudomonas aeruginosa
Factor C protein isolated from the horseshoe crab, Carcinoscorpius rotundicauda, has endotoxin binding capability. Synthetic peptides of 34 amino acids based on the sequence of two regions of factor C (Sushi 1 and Sushi 3) as well as their corresponding mutants exhibited activities against 30 clinical isolates of Pseudomonas aeruginosa. Collectively, all fou
American Society for Microbiology.
-
8. Enhancement of Neonatal Innate Defense: Effects of Adding an N-Terminal Recombinant Fragment of Bactericidal/Permeability-Increasing Protein on Growth and Tumor Necrosis Factor-Inducing Activity of Gram-Negative Bacteria Tested in Neonatal Cord Blood Ex Vivo
Innate defense against microbial infection requires the action of neutrophils, which have cytoplasmic granules replete with antibiotic proteins and peptides. Bactericidal/permeability-increasing protein (BPI) is found in the primary granules of adult neutrophils, has a high affinity for lipopolysaccharides (or “endotoxins”), and exerts selective cytotoxi
American Society for Microbiology.