Autoimune Diseases
Mostrando 13-21 de 21 artigos, teses e dissertações.
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13. Avaliação do efeito imunomodulador da isoflavona genisteína na encefalomielite autoimune experimental murina
Multiple sclerosis (MS) is the most common non-traumatic, disabling neurological human inflammatory demyelinating disease of the CNS. Experimental autoimmune encephalomyelitis (EAE) models MS and is characterized as a CD4+ Th1 cell-mediated autoimmune disease. Recent data show that estrogen plays a pivotal role in the immune response as well as in immune-med
Publicado em: 2007
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14. Estudo da relação entre o perfil genetico de diferentes sistemas de defesa contra xenobioticos nas doenças neoplasica e auto-imune da tiroide / Relationship study of the genetic profile of different xenobiotic systems in thyroid autoimmune and neoplastic diseases
Graves´s disease and differentiated thyroid cancer are multifactorial diseases with environmental and genetic interactions. Cigarette smoking is a well-recognized risk factor for Graves? disease and, particularly, for Graves? ophthalmopathy. Conversely, epidemiologic studies have consistently reported a reduced risk of differentiated thyroid cancer in tobac
Publicado em: 2007
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15. Efeito da crotapotina na evolução clinica da neurite experimental autoimune (EAN) / Effect of crotapotin on clinical evolution of experimental autoimmune neuritis
Biomedical research in which venom components are being investigated for their potential as novel therapeutic agents has emerged as an interesting option. Crotapotin which is a fraction of the venom of the rattlesnake Crotalus durissus terrificus, has been described as an antinflammatory that acts on the innate arm of the immune response. Here we have demons
Publicado em: 2006
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16. Perfil do HLA de classe II de pacientes com hepatite C e características de hepatite auto-imune / Class II HLA profile oh hepatitis C patients with autoimmune hepatitis features
Introduction: HCV chronic infection is an epidemic condition that affects more than 170 million of people around the world, and often is associated with autoimmunity phenomena. The role of HLA class II alleles has been studied in many autoimmune diseases. Aim: To investigate the presence of laboratory markers of autoimmunity and compatible anatomo pathologic
Publicado em: 2006
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17. 99m Tc-sestamibi thyroid uptake in euthyroid individuals and in patients with autoimmune thyroid disease / Avaliação da captação tireoidiana de sestamibi-99m Tc em individuos eutireoidianos e em portadores de doença tireoidiana auto-imune
Introdução: Múltiplos radioisótopos estão disponíveis para avaliar pacientes com doença tireoidiana. O iodeto radioativo e o pertecnetato-99m Tc são os traçadores mais utilizados com esta finalidade. Outros radiofármacos, como por exemplo, o sestamibi-99mTc também são captados pela glândula tireóide normal. No entanto, a biocinética de captaç
Publicado em: 2006
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18. Evidencias de doença tireoideana cronica subclinica em portadoras da sindrome de Turner / Evidences for subclinical chronic thyroid disease in patients with Turner Syndrome
O seguimento de pacientes com síndrome de Turner (ST) fteqüentemente revela alterações transitórias, recorrentes e assintomáticas de TSH e(ou) hormônios tireoideanos (HT). O objetivo deste trabalho foi avaliar estrutura e função da tireóide de portadoras da ST com história de alterações subclínicas nas concentrações hormonais. A casuística i
Publicado em: 2005
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19. Crescimento, desenvolvimento puberal e densidade mineral ossea em pacientes portadores de hepatite auto-imune na faixa etaria pediatrica
Autoimmune hepatitis (AIH) is a chronic inflammatory disease with unknown etiology; it causes a progressive destruction of the liver parenchyma, with progression to cirrhosis. Usually, the treatment is based in corticotherapy associated with Azathioprine. Among the side effects of the corticotherapy are osteoporosis, growth and development failure. Moreover,
Publicado em: 2005
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20. Avaliação da imunomodulação de citocinas e componentes apoptoticos por gangliosideos na encefalomielite experimental autoimune
The multiple sclerosis is a chronic inflammatory disease of the central nervous system (SNC), which autoreactive T cells drive immune response against myelin antigens. The relapses and remissions of the disease are responsible for the permanent neurological deficits. The observation of an aberrant inflammatory response against myelin epitopes suggests autoim
Publicado em: 2004
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21. Doença tiroideana auto-imune : expressão de colageno IV e laminina e relação com anti-corpos circulantes antimembrana basal
The purpose of the present study is to evaluate serological and morphologic aspects concerning the basement membrane (BM) of the thyroid follicle in autoimmune thyroid disease (ATD). In this way, new elements for ~ better understanding of its pathophisiology could be suggested. In order to detect antibodies to collagen IV and laminin, two major components of
Publicado em: 1994