Asymmetric Loss Function
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Banco Central e preferências assimétricas : uma aplicação de sieve estimators para os EUA e o Brasil
Uma questão interessante na política monetária é se os Bancos Centrais dão pesos iguais para desvios positivos e negativos da inflação e do hiato do produto das suas respectivas metas. Para responder à esta questão, estimou-se a função perda da autoridade monetária não parametricamente através do método de sieve estimator, expandindo-a atravé
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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2. Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila
Asymmetric divisions with two different division orientations follow different polarity cues for the asymmetric segregation of determinants in the sensory organ precursor (SOP) lineage. The first asymmetric division depends on frizzled function and has the mitotic spindle of the pI cell in the epithelium oriented along the anterior–posterior axis, giv
The National Academy of Sciences.
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3. A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries
Although the vertebrate embryonic midline plays a critical role in determining the left/right asymmetric development of multiple organs, few genes expressed in the midline are known to function specifically in establishing laterality patterning. Here we show that a gene encoding protein disulfide isomerase P5 (PDI-P5) is expressed at high levels in the organ
Cold Spring Harbor Laboratory Press.
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4. Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo
During asymmetric cell division, the membrane-associated Numb protein localizes to a crescent in the mitotic progenitor and is segregated predominantly to one of the two daughter cells. We have identified a putative serine/threonine kinase, Numb-associated kinase (Nak), which interacts physically with the phosphotyrosine binding (PTB) domain of Numb. The PTB
American Society for Microbiology.
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5. Conservation and molecular dissection of ROUGH SHEATH2 and ASYMMETRIC LEAVES1 function in leaf development
Maize ROUGH SHEATH2 (RS2) and Arabidopsis ASYMMETRIC LEAVES1 (AS1) are orthologous Myb-related genes required for leaf development and act as negative regulators of class 1 KNOTTED1-like homeobox (KNOX) genes in leaf primordia. Expression of RS2 in Arabidopsis fully complements as1 leaf phenotypes and represses the expression of the KNOX gene KNAT1 in
National Academy of Sciences.
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6. A family of Snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions
Three snail family genes snail, escargot and worniu, encode related zinc finger transcription factors that mediate Drosophila central nervous system (CNS) development. We show that simultaneous removal of all three genes causes defective neuroblast asymmetric divisions; inscuteable transcription/translation is delayed/suppressed in the segmented CNS. Further
Oxford University Press.
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7. Functional Interactions of Neurogenic Genes of Drosophila Melanogaster
The neurogenic genes of Drosophila melanogaster are involved in the decision of ectodermal cells to take on a neural or an epidermal fate. We present evidence in support of the notion that six of the neurogenic genes are functionally related. We studied the phenotype of embryos lacking one of the neurogenic genes in the presence of an increased dosage of the
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8. Role of Transcription in the Temporal Control of Development in Caulobacter crescentus
The requirement for transcription during development of the stalked bacterium, Caulobacter crescentus, was studied with synchronous cultures of swarmer cells. The developmental pattern in these bacteria was first established by determination of the times at which specific changes in cell structure and function occurred. These changes could be divided into th
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9. Role of SpoVG in Asymmetric Septation in Bacillus subtilis
Deletion of the citC gene, coding for isocitrate dehydrogenase, arrests sporulation of Bacillus subtilis at stage I after bipolar localization of the cell division protein FtsZ but before formation of the asymmetric septum. A spontaneous extragenic suppressor mutation that overcame the stage I block was found to map within the spoVG gene. The suppressing mut
American Society for Microbiology.
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10. In vivo analysis of the Saccharomyces cerevisiae centromere CDEIII sequence: requirements for mitotic chromosome segregation.
In the yeast Saccharomyces cerevisiae, the complete information needed in cis to specify a fully functional mitotic and meiotic centromere is contained within 120 bp arranged in the three conserved centromeric (CEN) DNA elements CDEI, -II, and -III. The 25-bp CDEIII is most important for faithful chromosome segregation. We have constructed single- and double
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11. The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development
In mammalian cells, the p38 mitogen-activated protein kinase (MAPK) pathway is activated in response to a variety of environmental stresses and inflammatory stimuli. However, the role of p38 MAPK signaling in unchallenged conditions remains largely unknown. We have isolated mutations in a Drosophila p38 MAPKK gene homolog, licorne (lic), and show that during
Cold Spring Harbor Laboratory Press.
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12. Phosphorylation of the Par Polarity Complex Protein Par3 at Serine 962 Is Mediated by Aurora A and Regulates Its Function in Neuronal Polarity*
The Aurora kinases are a family of serine/threonine protein kinases that perform important functions during the cell cycle. Recently, it was shown that Drosophila Aurora A also regulates the asymmetric localization of Numb to the basal and the partitioning-defective (Par) complex to the apical cortex of neuroblasts by phosphorylating Par6. Here, we show that
American Society for Biochemistry and Molecular Biology.