Astrocytomas
Mostrando 1-12 de 58 artigos, teses e dissertações.
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1. Pattern recognition of abscesses and brain tumors through MR spectroscopy: Comparison of experimental conditions and radiological findings
Abstract Introduction The interpretation of brain tumors and abscesses MR spectra is complex and subjective. In clinical practice, different experimental conditions such as field strength or echo time (TE) reveal different metabolite information. Our study aims to show in which scenarios magnetic resonance spectroscopy can differentiate among brain tumors,
Res. Biomed. Eng.. Publicado em: 17/08/2017
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2. Expression of estrogen and progesterone receptors in astrocytomas: a literature review
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones. A literature review for the presence of estrogen and progesterone receptors in astrocytomas was conducted in the PubMed database using the following MeSH terms: “estrogen
Clinics. Publicado em: 2016-08
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3. Vascular endothelial growth factor and KIT expression in relation with microvascular density and tumor grade in supratentorial astrocytic tumors
PURPOSE: To evaluate the relationship between microvascular density and the expression of vascular endothelial growth factor (VEGF) and KIT as possible markers of angiogenic stimulus in astrocytic tumors and correlate it with histopathological grading. METHODS: We enrolled 99 surgical specimens of supratentorial astrocytic tumors for analysis of VEGF and KIT
Acta Cir. Bras.. Publicado em: 2013-01
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4. Manual and semi-automatic quantification of in vivo ¹H-MRS data for the classification of human primary brain tumors
In vivo proton magnetic resonance spectroscopy (¹H-MRS) is a technique capable of assessing biochemical content and pathways in normal and pathological tissue. In the brain, ¹H-MRS complements the information given by magnetic resonance images. The main goal of the present study was to assess the accuracy of ¹H-MRS for the classification of brain tumors i
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-04
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5. Metabolism and brain cancer
Cellular energy metabolism is one of the main processes affected during the transition from normal to cancer cells, and it is a crucial determinant of cell proliferation or cell death. As a support for rapid proliferation, cancer cells choose to use glycolysis even in the presence of oxygen (Warburg effect) to fuel macromolecules for the synthesis of nucleot
Clinics. Publicado em: 2011
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6. Análise de polimorfismos em tumores gliais humanos / Polymorphisms Analysis in Human Glial Tumors
The Central nervous system tumors represent about 2% of all cancers. Although the incidence of CNS tumors is small compared with other cancers, these tumors are among the most serious human malignancies, because they affect the body responsible for coordination and integration of all organic activities. Gliomas are the most common tumors of the CNS. Despite
Publicado em: 2011
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7. Alterações metabólicas e o papel da mitocôndria no processo de tumorigênese de astrocitomas humanos / Metabolic alterations and the role of mitochondria in tumorigenic process of human astrocytomas
Mitochondria has a key role in cell survival and death. Mitochondrial DNA (mtDNA) alterations, for example, amplification, homoplasmic mutation, deletion and depletion, and their clinical and pathological implications have been analyzed in human malignancies. In order to search for mitochondrial alterations associated to tumorigenesis, this study aimed to an
Publicado em: 2010
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8. Análise da expressão, amplificação e deleção de EGFR e sua co-expressão com IL13R2 em astrocitomas / Analysis of EGFR expression, amplification and deletion and its coexpression with IL13R 2 in astrocytomas
O Receptor do Fator de Crescimento Epidérmico (do inglês, EGFR) é uma proteína de membrana celular que consiste em um domínio extracelular para o acoplamento do ligante e em um domínio intracelular apresentando sítio catalítico de tirosinoquinase. Em ~40% dos GBMs primários é observada a amplificação de EGFR resultando na sua hiperexpressão, o q
Publicado em: 2009
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9. Polymorphisms of EGF e EGFR genes in diffusely infiltrative astrocytomas / Estudo de polimorfismos dos genes EGF e EGFR em astrocitomas difusamente infiltrativos
INTRODUÇÃO: Os astrocitomas difusamente infiltrativos são os tumores mais freqüentes de Sistema Nervoso Central (SNC) com uma taxa de 5-7 novos casos por 100.000 pessoas ano. São tumores altamente invasivos e estão associados com alterações de alguns genes como EGF (fator de crescimento epidérmico) e o EGFR (receptor do fator de crescimento epidérm
Publicado em: 2008
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10. Espectroscopia de prÃtons por ressonÃncia magnÃtica na avaliaÃÃo da graduaÃÃo histolÃgica dos astrocitomas encefÃlicos
O objetivo foi revisar as principais aplicaÃÃes da espectroscopia de prÃtons por ressonÃncia magnÃtica (1H+ ERM) associada à imagem por ressonÃncia magnÃtica (IRM), na avaliaÃÃo dos astrocitomas encefÃlicos, enfatizando seu desempenho na graduaÃÃo tumoral, segundo os critÃrios da OrganizaÃÃo Mundial de SaÃde. Foram selecionados 54 artigos, p
Publicado em: 2006
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11. Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas.
Malignant astrocytomas, which are highly invasive, vascular neoplasms, compose the majority of nervous system tumors in humans. Elevated expression of fibroblast growth factors (FGFs) in astrocytomas has implicated the FGF family of mitogens in the initiation and progression of astrocyte-derived tumors. In this study, we demonstrated that human astrocytomas
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12. Neural cell adhesion molecule L1 in gliomas: correlation with TGF-beta and p53.
AIMS: To assess immunohistochemically whether the neural cell adhesion molecule L1, which is a member of the immunoglobulin superfamily and has been shown recently to be a stimulating factor for glioma migration, is expressed in glioma tissues, and to investigate factors that can regulate this expression. METHODS: Twenty seven glioma tissue specimens includi