Vitiligo - Part 2 - classification, histopathology and treatment
AUTOR(ES)
Faria, Adriane Reichert, Tarlé, Roberto Gomes, Dellatorre, Gerson, Mira, Marcelo Távora, Castro, Caio Cesar Silva de
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2014-09
RESUMO
In an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.
