Vitamin B12 absorption studies: effect of parenteral non-radioactive vitamin B12 on serum level of 57Co vitamin B12

AUTOR(ES)
RESUMO

The intestinal absorption of 57Co vitamin B12 has been measured by counting the radioactivity in the serum, and the effect of the parenteral administration of 1 mg. non-radioactive vitamin B12 two hours after the oral dose has been studied. When parenteral vitamin B12 was not given, the mean radioactivity in the serum was lower in both patients with pernicious anaemia and in control subjects, and the results in the patients with pernicious anaemia were more definitive. There was no significant difference between the results obtained with an Ekco scaler and those with an I.D.L. scaler.

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