Utilization of Carbon- and Nitrogen-containing Compounds for Neomycin Production by Streptomyces fradiae
AUTOR(ES)
Majumdar, Mrinal K.
RESUMO
A number of carbon and nitrogen compounds were tested for their effect on growth of Streptomyces fradiae 3535 and neomycin production. Dextrin, starch, and maltose were excellent carbon sources for neomycin production, and sodium nitrate, aspartic acid, and glutamic acid were adequate nitrogen sources. Studies on biochemical changes during fermentation in four typical media indicated that there was no direct relation between the growth of the organism and neomycin formation. The pH of the medium might be an important factor for neomycin synthesis. The quantitative formation of neomycin components depended on the variation of carbon and nitrogen sources. On the basis of this study, a suitable synthetic medium for neomycin production has been developed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=547052Documentos Relacionados
- ANTIMICROBIAL ACTION OF NITROGEN-CONTAINING STEROIDS
- Nitrogen-Containing and Carbohydrate-Containing Antigen from Actinomyces bovis
- Differential susceptibility of yeast and hyphal forms of Candida albicans to macrophage-derived nitrogen-containing compounds.
- Effects of Minerals on Neomycin Production by Streptomyces fradiae
- Utilization of Carbon and Nitrogen Sources by Streptomyces kanamyceticus for Kanamycin Production
