Trichotillomania: a good response to treatment with N-acetylcysteine

AUTOR(ES)

Barroso, Livia Ariane Lopes, Sternberg, Flavia, Souza, Maria Natalia Inacio de Fraia e, Nunes, Gisele Jacobino de Barros

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

2017-08

RESUMO

Abstract: Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a more favorable clinical course. The scalp, eyebrows and eyelashes are the most commonly affected sites. Glutamate modulating agents, such as N-acetylcysteine, have been shown to be a promising treatment. N-acetylcysteine acts by reducing oxidative stress and normalizing glutaminergic transmission. In this paper, we report a case of trichotillomania with an excellent response to N-acetylcysteine.

Documentos Relacionados

• Death from paracetamol overdose despite appropriate treatment with n‐acetylcysteine
• N-acetylcysteine in the treatment of skin-picking disorder
• Systematic review of N-acetylcysteine in the treatment of addictions
• N-acetylcysteine in clinical sepsis: a difficult marriage
• N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition