Transmissible Mink Encephalopathy: Studies on the Peripheral Lymphocyte
AUTOR(ES)
Marsh, R. F.
RESUMO
Circulating lymphocytes from mink with transmissible mink encephalopathy were studied for the presence of virus particles and for infectivity. Electron microscope examination of phytohemagglutinin-stimulated lymphocyte cultures revealed no evidence of virus-like particles. Circulating lymphocytes were also found to be noninfectious when the transmissible agent could be demonstrated in intact lymphoid organs in infected mink. A lymphopenia was detected in affected mink during the late clinical stage of disease, but this was most likely a secondary effect due to a terminal stress factor.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=422682Documentos Relacionados
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