Transforming growth factor beta 1 as a prognostic factor in pulmonary adenocarcinoma.
AUTOR(ES)
Takanami, I
RESUMO
AIMS--To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. METHODS--TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. RESULTS--Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. CONCLUSIONS--TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=502200Documentos Relacionados
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