Toll-like receptors: a family of pattern-recognition receptors in mammals

AUTOR(ES)

Armant, Myriam A

FONTE

BioMed Central

RESUMO

Toll-like receptors are a family of pattern-recognition receptors in mammals that can discriminate between chemically diverse classes of microbial products, including bacterial cell-wall components, and that can elicit pathogen-specific cellular immune responses. Toll-like receptors share characteristic features with the interleukin-1 and interleukin-18 cytokine receptors and these receptor classes activate similar signal-transduction pathways.

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