The Presence of Ribonucleotides in Mature Closed-Circular Mitochondrial DNA
AUTOR(ES)
Grossman, Lawrence I.
RESUMO
Mitochondrial DNA from mouse and HeLa cells is nicked by alkali and chick-embryo ribonuclease H. It has been concluded that ribonucleotides are present in the closed-circular duplex. A comparative study of the scission rates at pH 13.0 of RNA and of mitochondrial DNAs indicates that there are no more than 10 ribonucleotides in the major fraction of the mitochondrial DNAs.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=427232Documentos Relacionados
- A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate
- DNA synthesis in polyoma virus infection. IV. Mechanism of formation of closed-circular viral DNA deficient in superhelical turns.
- Amplification of closed circular DNA in vitro.
- Amplification of closed circular DNA in vitro.
- A DYE-BUOYANT-DENSITY METHOD FOR THE DETECTION AND ISOLATION OF CLOSED CIRCULAR DUPLEX DNA: THE CLOSED CIRCULAR DNA IN HELA CELLS
