Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives

AUTOR(ES)

Sridhara, Ajjanna M, Reddy, Kallam R. Venugopala, Keshavayya, Jathi, Ambika, Dasannana Malige S, Gopinath, Vadiraj S, Bose, Prosenjit, Goud, Sanath Kumar, Peethambar, Sanenahalli K

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2011-05

RESUMO

Uma série de novas 3-isoxazolinas substituídas, derivadas do metil-3-metóxi-2-(4-oxo-3,4-diidroftalazin-1-il)prop-2-enoato foram estudadas e sintetizadas a partir do metil-(4-oxo-3,4-diidroftalazin-1-il)acetato, o qual foi preparado a partir do anidrido ftálico. As estruturas dos novos compostos sintetizados foram caracterizadas por dados espectrais e suas atividades antimicrobianas e citotóxicas estudadas. Vários desses compostos mostraram boa atividade antimicrobiana

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