Spontaneous canine hydrocephalus: cerebrospinal fluid dynamics1
AUTOR(ES)
Sahar, A.
RESUMO
Cerebrospinal fluid dynamics were studied in 14 dogs with spontaneous hydrocephalus. In nine of the dogs aqueductal obstruction was observed and the remainder had a `communicating type' hydrocephalus. The major histological findings consisted of severe ependymal destruction, spongy changes in the periventricular white matter, increased density of capillaries in this area, and varying degrees of thickening, fibrosis, and fusion of the choroid villi. The formation and absorption of CSF were studied by perfusion of the cerebral ventricles. The rate of formation of CSF was found to decrease with perfusion pressure by Vf = 0·02595−0·00022 P ml./min (P = pressure in cm H2O). The absorption of spinal fluid was found to increase linearly with pressure by Va = 0·0165 + 0·00050 P. The various factors influencing the formation and absorption of the spinal fluid are discussed. The meaning and attainment of `arrest' of the hydrocephalic process in terms of the measured rates of CSF formation and absorption in these animals are considered.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1083469Documentos Relacionados
- Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results.
- Cerebrospinal fluid shunt dynamics in patients with idiopathic adult hydrocephalus syndrome.
- Primary spontaneous cerebrospinal fluid rhinorrhoea1
- HYDROCEPHALUS AND THE CEREBROSPINAL FLUID
- Effect of cerebrospinal fluid shunts on intracranial pressure and on cerebrospinal fluid dynamics: 2. A new technique of pressure measurements: results and concepts1 3.A concept of hydrocephalus
