SPA: simple web tool to assess statistical significance of DNA patterns
AUTOR(ES)
Richard, H.
FONTE
Oxford University Press
RESUMO
Many statistical methods and programs are available to compute the significance of a given DNA pattern in a genome sequence. In this paper, after outlining the mathematical background of this problem, we present SPA (Statistic for PAtterns), an expert system with a simple web interface designed to be applied to two of these methods (large deviation approximations and exact computations using simple recurrences). A few results are presented, leading to a comparison between the two methods and to a simple decision rule in the choice of that to be used. Finally, future developments of SPA are discussed. This tool is available at the following address: http://stat.genopole.cnrs.fr/SPA/.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=169190Documentos Relacionados
- Strathpeffer Spa: Dr William Bruce and polymyalgia rheumatica
- LAX and SPA: Major regulators of shoot branching in rice
- Statistical significance of symmetrical and repetitive segments in DNA.
- O mundo não é um spa: sobre a ética do desejo na clínica da obesidade
- A simple apparatus to assess cutaneous thermal sensitivity