Resistance of Candida albicans biofilms to antifungal agents in vitro.
AUTOR(ES)
Hawser, S P
RESUMO
Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [3H]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy of the biofilms.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=162894Documentos Relacionados
- Effect of Growth Rate on Resistance of Candida albicans Biofilms to Antifungal Agents
- Antifungal Combinations against Candida albicans Biofilms In Vitro
- Exopolysaccharide matrix of developed candida albicans biofilms after exposure to antifungal agents
- In Vitro Pharmacodynamic Properties of Three Antifungal Agents against Preformed Candida albicans Biofilms Determined by Time-Kill Studies
- Standardized Method for In Vitro Antifungal Susceptibility Testing of Candida albicans Biofilms