Projeto e construção de placas espalhadoras e degradadoras de energia para  uso em radioterapia com feixes de elétrons para doenças de pele / Project and construction of energy degrading and scattering plates for electron beam radiotherapy for skin diseases

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

24/06/2010

RESUMO

There are many radiosensitive epidermotropics diseases such as mycosis fungoids and the syndrome of Sézary, coetaneous neoplasics originated from type T lymphocytes. Several studies indicate the eradication of the disease when treated with linear accelerators emitting electron beams with energies between 4 to 10 MeV. However, this treatment technique presents innumerable technical challenges since the disease in general reaches all patient´s body, becoming necessary not only a very large field size radiation beam, but also deliver superficial doses limited to the skin depth. To reach the uniformity in the dose distribution, many techniques had already been developed. Based on these previous studies and guided by the report n. 23 of the American Association of Physicists in Medi-cine (AAPM), the present study developed an energy scattering and degrading plates and made dosimetry (computational and experimental), supplying subsidies for a future installation of Total Skin Electron Therapy (TSET) at the Serviço de Radioterapia do Hospital das Clínicas de São Paulo. As part of the plates design, first of all, the energy spectrum of the 6 MeV electron beam of the VARIAN 2100C accelerator was reconstructed through Monte Carlo simulations using the MCNP4C code and based on experimental data. Once the spectrum is built, several materials were analyzed for the plates design based on radial and axial dose distribution, production of rays-x and dose attenuation. The simulation results were validated by experimental measurements in order to obtain a large field of radiation with 200 cm x 80 cm that meets the specifications of the AAPM protocol.

ASSUNTO(S)

mcnp método de monte carlo monte carlo method radioterapia radiotherapy tset tset coetaneous neoplasics linfoma cutâneo mcnp

ACESSO AO ARTIGO

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