Prevalence and genotype distribution of human papillomavirus: implications for cancer screening and vaccination in Henan province, China

AUTOR(ES)

Zhao, Jun-Wei, Xu, Jing-Jing, Yan, Min, Sun, Xiao-Xu, Shi, Guang, Ming, Liang

FONTE

Rev. Soc. Bras. Med. Trop.

DATA DE PUBLICAÇÃO

2016-04

RESUMO

Abstract: INTRODUCTION: To provide information for cervical cancer screening and vaccination in Henan province, China, the distribution of human papillomavirus (HPV) was analyzed. METHODS: The HPV genotypes were detected using gene array and flow-through hybridization. RESULTS: Overall, 38.1% (1,536/4,033) of the women were human papillomavirus deoxyribonucleic acid (HPV DNA) positive. The prevalence of high-risk HPV types was 32.4%. HPV 16 was the most prevalent genotype (8.9%), followed by HPV 52 (5.8%) and HPV 58 (4.4%). CONCLUSIONS: The data support close surveillance of women for cervical cancer screening, and HPV prophylactic vaccines including HPV16, HPV 52, and HPV 58 might offer greater protection in this area.

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