Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa

AUTOR(ES)

Ferraz, Helena O., Silva, Magali G., Carvalho, Rui, Suffredini, Ivana B., Kato, Edna T. M., Arakaki, Fernanda, Bacchi, Elfriede M.

FONTE

Revista Brasileira de Farmacognosia

DATA DE PUBLICAÇÃO

26/11/2010

RESUMO

Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test.

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